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Gene Expression Data
Assay Details
Assay
Reference: J:75699 Albrecht AN, et al., The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
Assay type: RNA in situ
MGI Accession ID: MGI:5446492
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Probe: Col2a1 probe6
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen not shown 13.5 wt: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand Present

Specimen not shown 13.5 spdh/spdh: embryonic day 13.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS21: forelimb digit Present Widespread Strong expression throughout digits.

Specimen 4 Col2 Newborn wt: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: hand bone Present Regionally restricted 4_Col2 Newborn wt Expression in resting, proliferating and pre-hypertrophic chondrocytes. No expression in hypertrophic chondrocytes.
TS27: hand joint Absent 4_Col2 Newborn wt No expression in developing joint space

Specimen 4 Col2 Newborn spdh/spdh: postnatal newborn; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS27: forelimb digit Strong Widespread 4_Col2 Newborn spdh/spdh Strong expression throughout digits.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory