Gene Expression Data
Assay Details
Assay
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Reference:
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J:93610
Harrelson Z, et al., Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development. Development. 2004 Oct;131(20):5041-52
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5445988
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Gene symbol:
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Myh7
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Gene name:
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myosin, heavy polypeptide 7, cardiac muscle, beta
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Results
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Specimen
+/-:
embryonic day 9.5; Tbx2tm1Pa/Tbx2 +
(more )
Specimen
+/-:
(close )
Genetic Background:
|
either: (involves: 129) or (involves: 129 * C57BL/6NTac * ICR)
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Mutant Allele(s):
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Tbx2tm1Pa/Tbx2+
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Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: heart |
Present |
Regionally restricted |
5M
|
The posterior boundary of expression is found at the atrio-ventricular canal/left atrium boundary.
|
Specimen
-/-:
(close )
Genetic Background:
|
either: (involves: 129) or (involves: 129 * C57BL/6NTac * ICR)
|
Mutant Allele(s):
|
Tbx2tm1Pa/Tbx2tm1Pa
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: heart |
Present |
Regionally restricted |
5N
|
Expression in the mutant is found extending posterior of the boundary of expression is found in the wild type, suggesting a delay in transcriptional downregulation.
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