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Gene Expression Data
Assay Details
Assay
Reference: J:80954 Chapman DL, et al., Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6. Nature. 1998 Feb 12;391(6668):695-7
Assay type: RNA in situ
MGI Accession ID: MGI:5445888
Gene symbol: Pax6
Gene name: paired box 6
Probe: Pax6 probe28
Probe preparation: Antisense RNA
Results
Specimen normal: embryonic day 10.5 (more )
Note: transverse section
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4d left Expression is present in the lateral ventricular regions.

Specimen Tbx6-mutant: embryonic day 10.5; Tbx6tm1Pa/Tbx6tm1Pa (more )
Note: transverse section
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4d right Expression is present in the lateral ventricular regions. In the mutants, expression is present in the correct dorsal-ventral pattern in the neural tube and additional paraxial tubes but is not expressed in the paraxial tissue rostral to the forelimb.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory