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Gene Expression Data
Assay Details
Assay
Reference: J:57065 Wood HB, et al., Comparative expression of the mouse Sox1, Sox2 and Sox3 genes from pre-gastrulation to early somite stages. Mech Dev. 1999 Aug;86(1-2):197-201
Assay type: RNA in situ
MGI Accession ID: MGI:5444678
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Results
Specimen 1 PS: embryonic day 6.5 (more )
Note: Pre-streak stage.
Structure Level Pattern Image Note
TS9: embryo ectoderm Present Widespread 1_Sox2 PS Expression thoughout epiblast.
TS9: extraembryonic ectoderm Present Regionally restricted 1_Sox2 PS Expression in band of extraembryonic ectoderm abutting embryonic/extraembryonic boundary.
Specimen 1 MS-LS: embryonic day 7.0 (more )
Note: Midstreak / late streak stage.
Structure Level Pattern Image Note
TS10: embryo ectoderm Present Regionally restricted 1_Sox2 MS-LS Embryonic expression restricted to anterior ectoderm.
TS10: extraembryonic component Present Regionally restricted 1_Sox2 MS-LS Extraembryonic expression confined to chorion.
Specimen 1 LB: embryonic day 7.5 (more )
Note: Late allantoic bud / neural plate stage.
Structure Level Pattern Image Note
TS11: embryo ectoderm Present Regionally restricted 1_Sox2 LB Extraembryonic expression confined to chorion.
Specimen 1 HF: embryonic day 7.5 (more )
Note: Head fold stage.
Structure Level Pattern Image Note
TS11: embryo ectoderm Present Regionally restricted 1_Sox2 HF Strongest expression in anterior ectoderm.
Specimen 2A 1-3s: embryonic day 8.0 (more )
Note: 1-3 somite stage.
Structure Level Pattern Image Note
TS12: embryo ectoderm Present Regionally restricted 2A Sox2 1-3s Expression in neurectoderm from the onset of somitogenesis; upregulated in ectoderm overlying the primitive streak.
Specimen 2A 6s: embryonic day 8.0 (more )
Note: 6 somite stage.
Structure Level Pattern Image Note
TS12: rhombomere Present Regionally restricted 2A Sox2 6s Expression downregulated in zone corresponding to rhombomeres 5 and 6.
Specimen 2B 6s: embryonic day 8.0 (more )
Note: 6 somite stage.
Structure Level Pattern Image Note
TS12: rhombomere Present Regionally restricted 2B Sox2 6s Expression downregulated in zone corresponding to rhombomeres 5 and 6.
Specimen 2B 8-10s: embryonic day 8.5 (more )
Note: 8-10 somite stage.
Structure Level Pattern Image Note
TS13: surface ectoderm Present Regionally restricted 2B Sox2 8-10s Expression in ectoderm overlying 1st and 2nd branchial arches.
Specimen 2B 12-14s: embryonic day 9.0 (more )
Note: 12-14 somite stage.
Structure Level Pattern Image Note
TS14: surface ectoderm Present Regionally restricted 2B Sox2 12-14s Expression in ectoderm overlying 1st and 2nd branchial arches.
Specimen 2C b: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: surface ectoderm Present Regionally restricted 2C b Expression in a region of surface ectoderm adjacent to the hindbrain.
TS12: gut endoderm Present 2C b
Specimen 2C e: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: olfactory placode Present 2C e
Specimen 2C h: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: otic placode Present Regionally restricted 2C h Expression in ventral half of otic placode.
Specimen not shown: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: neural tube floor plate Absent
TS14: neural tube roof plate Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory