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Gene Expression Data
Assay Details
Assay
Reference: J:22210 Robinson GW, et al., Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development. Mech Dev. 1994 Dec;48(3):199-215
Assay type: RNA in situ
MGI Accession ID: MGI:5441365
Gene symbol: Dlx3
Gene name: distal-less homeobox 3
Probe: Dlx3 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5A/B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: 1st branchial arch Present Regionally restricted 5A/B Expression is in the posterior portion of the arch. The lateral extent of expression ends at the branchial pouch.
TS19: 2nd branchial arch Present Regionally restricted 5A/B Expression is in the posterior portion of the arch. The lateral extent of expression ends at the branchial pouch.

Specimen 5C/D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mandibular process mesenchyme Present 5C/D Expression is mainly found in mesenchymal cells.
TS20: head mesenchyme Present Regionally restricted 5C/D Expression is present in the lateral region of the first and second arch. Expression is mainly in mesenchymal cells.

Specimen 5E/F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: outer ear Present 5E/F Expression is present in the mesenchyme abutting the first branchial cleft; this is the area from which the external ear develops.

Specimen 5G/H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: nasal capsule Present 5G/H
TS21: nasal cavity epithelium Present Regionally restricted 5G/H Expression is present in the respiratory epithelium of the naris; there is no expression in the more internal sensory epithelium.

Specimen 5I/J: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: middle ear mesenchyme Weak Diffuse 5I/J

Specimen 6C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear vestibular component Present 6C

Specimen 6D/E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: utricle epithelium Present 6D/E
TS21: semicircular canal epithelium Present 6D/E
TS21: saccule Absent 6D/E

Specimen 6H/I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: semicircular canal Present Non-Uniform 6H/I
TS21: utricle Present 6H/I

Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: upper jaw mesenchyme Present Single cells
TS22: semicircular canal Absent

Specimen 7E/F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw molar mesenchyme Strong 7E/F Expression is present in the mesenchyme of the dental papilla.

Specimen 7I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: incisor Present 7I Areas of expression include the follicular mesenchyme.

Specimen 7L: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: incisor enamel organ Present Regionally restricted 7L Expression is present in the ameloblast layer.
TS24: incisor mesenchyme Present Regionally restricted 7L Expression is present in odontoblasts.

Specimen 8C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vibrissa Present Graded 8C The follicles differentiate in an anterior-posterior sequence; the expression levels seen are consistent with that.

Specimen 8F/G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa Strong Regionally restricted 8F/G Expression is seen in the matrix cells.

Specimen Not shown: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: vibrissa Present Regionally restricted Expression is seen in the matrix cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory