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Gene Expression Data
Assay Details
Assay
Reference: J:70831 Becker MB, et al., Irx1 and Irx2 expression in early lung development. Mech Dev. 2001 Aug;106(1-2):155-8
Assay type: RNA in situ
MGI Accession ID: MGI:5439966
Gene symbol: Irx2
Gene name: Iroquois homeobox 2
Probe: Irx2 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future hindbrain Present 1B
TS13: foregut diverticulum Weak Regionally restricted 1B Weak expression was detected in the anterior foregut at the dorsal-caudal side of the heart.
Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lung epithelium Present 1D
TS17: lung mesenchyme Absent 1D
Specimen 2B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lobar bronchus Present Regionally restricted 2B Expression was detected in the distal tips of the segmental bronchi. Expression covers the complete separation zone of forming lung buds.
Specimen 2D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lobar bronchus Present Regionally restricted 2D Expression was dramatically decreased at E13.5 in all five lobes of the lung. Only single expressing buds at the margin of the lobes were detected.
Specimen 2F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung Absent 2F
Specimen 2H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung epithelium Present 2H
Specimen 2J: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Present 2J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory