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Gene Expression Data
Assay Details
Assay
Reference: J:70831 Becker MB, et al., Irx1 and Irx2 expression in early lung development. Mech Dev. 2001 Aug;106(1-2):155-8
Assay type: RNA in situ
MGI Accession ID: MGI:5439964
Gene symbol: Irx1
Gene name: Iroquois homeobox 1
Probe: Irx1 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future midbrain Present 1A
TS13: foregut diverticulum Present Widespread 1A The center of expression is dorsal to the developing heart at the side of lung induction.
Specimen 1C: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: main bronchus epithelium Present 1C
TS16: main bronchus mesenchyme Absent 1C
Specimen 2A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lobar bronchus Present Regionally restricted 2A Expression was detected in the distal tips of the segmental bronchi.
Specimen 2C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lobar bronchus Strong Regionally restricted 2C Expression was detected in all lobes.
Specimen 2E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung Present Regionally restricted 2E Expression was concentrated at the rim whereas it starts to decline in the center of the five lobes.
Specimen 2G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung epithelium Present 2G
TS20: lung mesenchyme Absent 2G
Specimen 2I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Present 2I
TS21: lung mesenchyme Absent 2I
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory