Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:70830
Zelzer E, et al., Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2. Mech Dev. 2001 Aug;106(1-2):97-106
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:5439869
|
|
Gene symbol:
|
Runx2
|
|
Gene name:
|
runt related transcription factor 2
|
|
Probe:
|
Cbfa1 cDNA10
|
|
Probe preparation:
|
Antisense labelled with P33 RNA
|
|
|
Results
|
Specimen
5A/a:
embryonic day 15.0
(more  )
Specimen
5A/a:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 15.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: skeleton |
Present |
Regionally restricted |
5A/a
|
Expression was detected in chondrocytes, weakly in resting and proliferating chondrocytes, but progressively stronger as chondrocytes matured. No expression was seen near or at articular surfaces in cartilage or perichondrium.
|
Specimen
5B/b:
embryonic day 17.5
(more )
Specimen
5B/b:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 17.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS25: skeleton |
Present |
Regionally restricted |
5B/b
|
Expression was detected in the periosteum and in cartilage within the growth plate where it was upregulated as chondrocytes mature, but decreased markedly in terminal hypertrophic chondrocytes. Expression was high in developing trabecular bone.
|
|
Analysis Tools
