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Gene Expression Data
Assay Details
Assay
Reference: J:98391 Taketo T, et al., Expression of SRY proteins in both normal and sex-reversed XY fetal mouse gonads. Dev Dyn. 2005 Jun;233(2):612-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5438002
Gene symbol: Sry
Gene name: sex determining region of Chr Y
Antibody: anti-SRY (Mab #15)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to fluorescein
Results
Specimen 4a/b: embryonic day 11.8 (more )
Note: 22 tail somites. The authors identified this specimen as XY. Double labeled: green - Sry; red - Amh (assay MGI:5438005).
Structure Level Pattern Image Note
TS19: gonad Present Widespread 4a , 4b Expression is present in numerous cells in the entire genital ridge. Intense staining is seen in the nuclei.
Specimen 4c: embryonic day 11.6 (more )
Note: 21 tail somites. The authors identified this specimen as XY. Double labeled: green - Sry; red - Ddx4 (assay MGI:5438006).
Structure Level Pattern Image Note
TS19: gonad Present Regionally restricted 4c Expression is present in the nuclei of somatic cells surrouding the germ cells.
Specimen 4d/e/f: embryonic day 12.3 (more )
Note: 25 tail somites. The authors identified this specimen as XY. Double labeled: green - Sry; red - Amh (assay MGI:5438005).
Structure Cell Type Level Pattern Image Note
TS20: testis Strong Non-Uniform 4f , 4d Expression is present in the nuclei of cells in the posterior pole where the testis cords have not developed.
TS20: Sertoli cell Sertoli cell Present 4d , 4e Expression is seen in the Sertoli cells near the medial region.
Specimen 7a: embryonic day 11.8 (more )
Note: 18 tail somites. The authors identified this specimen as XY. Double labeled: green - Sry; red - Ddx4 (assay MGI:5438006).
Structure Level Pattern Image Note
TS19: gonad Present Regionally restricted 7a Expression is present in the nuclei of somatic cells around the germ cells.
Specimen 7b: embryonic day 12.3; X/SryPOS-TIR (more )
Note: 26 tail somites. Double labeled: green - Sry; red - Ddx4 (assay MGI:5438006).
Structure Level Pattern Image Note
TS20: gonad Present 7b Expression is present in the nuclei of somatic cells around the germ cells.
Specimen 7c/d: embryonic day 12.4 (more )
Note: 25 tail somites. The authors identified this specimen as XY. Double labeled: green - Sry; red - Amh (assay MGI:5438005).
Structure Level Pattern Image Note
TS20: testis Trace 7c
TS20: primary sex cord Present Single cells 7d , 7c Expression is present in the nuclei of a few cells.
Specimen 7e/f: embryonic day 13.4; X/SryPOS-TIR (more )
Note: This specimen is an ovatestis; testis is present in 60% of the gonad. Double labeled: green - Sry; red - Amh (assay MGI:5438005).
Structure Level Pattern Image Note
TS21: gonad Trace Single cells 7e , 7f
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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