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Gene Expression Data
Assay Details
Assay
Reference: J:39658 Buscher D, et al., Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development. Mech Dev. 1997 Mar;62(2):175-82
Assay type: RNA in situ
MGI Accession ID: MGI:5437847
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 cDNA13
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: In the figure only forelimbs were shown. The same expression pattern was also seen in hindlimbs.
Results
Specimen C left: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present Widespread 4C left Expressed in the whole apical ectodermal ridge.

Specimen C middle: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present Widespread 4C middle Expressed in the whole apical ectodermal ridge.

Specimen C right: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand Present Regionally restricted 4C right Expressed in the whole apical ectodermal ridge.

Specimen D left: embryonic day 10.5; Gli3Xt/Gli3Xt (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present Widespread 4D left Expression is the same as in the wild-type control. Expressed in the whole apical ectodermal ridge.

Specimen D middle: embryonic day 11.5; Gli3Xt/Gli3Xt (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present Widespread 4D middle Expressed in the whole apical ectodermal ridge. Expression was stronger in the most anterior region.

Specimen D right: embryonic day 12.5; Gli3Xt/Gli3Xt (more )
Structure Level Pattern Image Note
TS20: hand Present Regionally restricted 4D right Expressed in the whole apical ectodermal ridge. Expression was stronger in the most anterior region.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory