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Gene Expression Data
Assay Details
Assay
Reference: J:83659 Wright TJ, et al., Fgf3 and Fgf10 are required for mouse otic placode induction. Development. 2003 Aug;130(15):3379-90
Assay type: RNA in situ
MGI Accession ID: MGI:5435937
Gene symbol: Gbx2
Gene name: gastrulation brain homeobox 2
Probe: Gbx2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4M: embryonic day 8.0; Fgf3tm1Mrc/Fgf3+, Fgf10tm1Wss/Fgf10+ (more )
Note: Six somite-stage embryo.
Structure Level Pattern Image Note
TS12: otic placode Present 4M Expression is present in the presumptive otic ectoderm.
TS12: head mesenchyme Present Regionally restricted 4M Expression is present in the mesenchyme underlying the otic ectoderm.
Specimen 4N: embryonic day 8.0; Fgf3tm1Mrc/Fgf3+, Fgf10tm1Wss/Fgf10+ (more )
Note: Six somite-stage embryo. This section is through the otic region.
Structure Level Pattern Image Note
TS12: otic placode Present 4N
TS12: head mesenchyme Present Regionally restricted 4N Expression is present in the mesenchyme underlying the otic ectoderm.
Specimen 4O: embryonic day 8.0; Fgf3tm1Mrc/Fgf3tm1Mrc, Fgf10tm1Wss/Fgf10tm1Wss (more )
Note: Six somite-stage embryo.
Structure Level Pattern Image Note
TS12: head mesenchyme Present Regionally restricted 4O Expression is excluded from the dorsal (otic) region.
TS12: surface ectoderm Present Regionally restricted 4O Expression is excluded from the dorsal (otic) region.
Specimen 4P: embryonic day 8.0; Fgf3tm1Mrc/Fgf3tm1Mrc, Fgf10tm1Wss/Fgf10tm1Wss (more )
Note: Six somite-stage embryo. This section is through the otic region.
Structure Level Pattern Image Note
TS12: head mesenchyme Present Regionally restricted 4P Expression is excluded from the dorsal (otic) region.
TS12: surface ectoderm Present Regionally restricted 4P Expression is excluded from the dorsal (otic) region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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