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Gene Expression Data
Assay Details
Assay
Reference: J:123544 Hume CR, et al., Expression of LHX3 and SOX2 during mouse inner ear development. Gene Expr Patterns. 2007 Aug;7(7):798-807
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5431532
Gene symbol: Myo6
Gene name: myosin VI
Antibody: anti-myosin VI
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: saccule epithelium Present Regionally restricted Expression was detected in a small subset of cells.
Specimen 1D: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: saccule epithelium Present Regionally restricted 1D Expression was detected in the lumenal layer of the vestibular sensory epithelium.
Specimen 1H: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: saccule epithelium Present 1H
Specimen 1L: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: saccule epithelium Present 1L
Specimen 1P: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cochlea epithelium Absent 1P
Specimen 1S: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 1S Expression was detected in the organ of Corti at the basal end of the cochlea in a single row of cells adjacent to the lumen of the cochlear duct, corresponding to the inner hair cells.
Specimen 2D: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: saccule epithelium Present Regionally restricted 2D Expression was detected exclusively in the hair cell layer of the epithelium.
Specimen 2H: embryonic day 17.0 (more )
Note: Cochlea - base
Structure Level Pattern Image Note
TS25: cochlea Present Regionally restricted 2H Expression was detected in the basal cochlea in both inner and outer hair cells.
Specimen 2L: embryonic day 17.0 (more )
Note: Cochlea - middle
Structure Level Pattern Image Note
TS25: cochlea Present Regionally restricted 2L Expression was detected in the middle cochlea in both inner and outer hair cells.
Specimen 2P: embryonic day 17.0 (more )
Note: Cochlea - apex
Structure Level Pattern Image Note
TS25: cochlea Absent 2P Expression was not detected in the apical cochlea.
Specimen 2Q: embryonic day 17.0 (more )
Note: Double labeled: green - Myo6; red - Sox2 (assay MGI:5431543).
Structure Level Pattern Image Note
TS25: cochlea Present Regionally restricted 2Q Along the medial to lateral axis of the mid-basal cochlea, expression was detected in hair cells.
Specimen 3D: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: saccule epithelium Present Regionally restricted 3D Expression was detected in vestibular hair cells.
Specimen 3H: postnatal day 2 (more )
Note: Cochlea - base
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 3H Expression was detected along the entire axis of the cochlea in inner and outer hair cells.
Specimen 3L: postnatal day 2 (more )
Note: Cochlea - middle
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 3L Expression was detected along the entire axis of the cochlea in inner and outer hair cells.
Specimen 3P: postnatal day 2 (more )
Note: Cochlea - apex
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 3P Expression was detected along the entire axis of the cochlea in inner and outer hair cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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