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Gene Expression Data
Assay Details
Assay
Reference: J:123544 Hume CR, et al., Expression of LHX3 and SOX2 during mouse inner ear development. Gene Expr Patterns. 2007 Aug;7(7):798-807
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5431527
Gene symbol: Atoh1
Gene name: atonal bHLH transcription factor 1
Antibody: anti-MATH1
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: saccule epithelium Present Regionally restricted Expression was detected in a small subset of cells.
Specimen 1B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: saccule epithelium Present Regionally restricted 1B Expression was detected predominantly in the more lumenal layer corresponding to differentiating hair cells.
Specimen 1F: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: saccule epithelium Present 1F
Specimen 1J: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: saccule epithelium Present 1J
Specimen 1N: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cochlea epithelium Absent 1N
Specimen 1Q: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 1Q Expression was detected in the organ of Corti at the basal end of the cochlea in a single row of cells adjacent to the lumen of the cochlear duct, corresponding to the inner hair cells. Weak immunoreactivity in outer hair cell nuclei was also seen.
Specimen 2B: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: saccule epithelium Present Regionally restricted 2B Expression was detected exclusively in the hair cell layer of the epithelium.
Specimen 2F: embryonic day 17.0 (more )
Note: Cochlea - base
Structure Level Pattern Image Note
TS25: cochlea Present Regionally restricted 2F Expression was detected in the basal cochlea in both inner and outer hair cells.
Specimen 2J: embryonic day 17.0 (more )
Note: Cochlea - middle
Structure Level Pattern Image Note
TS25: cochlea Present Regionally restricted 2J Expression was detected in the middle cochlea in both inner and outer hair cells.
Specimen 2N: embryonic day 17.0 (more )
Note: Cochlea - apex
Structure Level Pattern Image Note
TS25: cochlea Absent 2N No expression was detected in the apical cochlea.
Specimen 3B: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: saccule epithelium Present Regionally restricted 3B Expression was detected in vestibular hair cells.
Specimen 3F: postnatal day 2 (more )
Note: Cochlea - base
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 3F Expression was detected along the entire axis of the cochlea in inner and outer hair cells.
Specimen 3J: postnatal day 2 (more )
Note: Cochlea - middle
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 3J Expression was detected along the entire axis of the cochlea in inner and outer hair cells.
Specimen 3N: postnatal day 2 (more )
Note: Cochlea - apex
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 3N Expression was detected along the entire axis of the cochlea in inner and outer hair cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory