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Gene Expression Data
Assay Details
Assay
Reference: J:131720 Aquino JB, et al., Differential expression and dynamic changes of murine NEDD9 in progenitor cells of diverse tissues. Gene Expr Patterns. 2008 Apr;8(4):217-26
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5428873
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2
Detection system: Secondary antibody coupled to Cy2
Results
Specimen 2C: embryonic day 10.5 (more )
Note: Triple labeled: green - Sox2; red - Nedd9 (assay MGI:5428867); blue - Sox10 (assay MGI:5428874).
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 2C Expression was detected in progenitors in the neuroepithelium.

Specimen 3B: embryonic day 10.5 (more )
Note: Double labeled: green - Sox2; red - Nedd9 (assay MGI:5428867).
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 3B Expression was detected in the ventral midbrain and in the prospective occulomotor nuclei.

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted Expression was detected in neuroepithelial cells.

Specimen 4A: embryonic day 12.5 (more )
Note: Double labeled: green - Sox2; red - Nedd9 (assay MGI:5428867).
Structure Level Pattern Image Note
TS20: pons ventricular layer Present 4A There was some overlap with Nedd9 expression.

Specimen 4E: embryonic day 10.5 (more )
Note: Double labeled: green - Sox2; red - Nedd9 (assay MGI:5428867).
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 4E Expression was detected in the dorsal motor nucleus of the vagus nerve.

Specimen 4F: embryonic day 10.5 (more )
Note: Double labeled: green - Sox2; red - Nedd9 (assay MGI:5428867).
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 4F Expression was detected in the hypoglossal nucleus.

Specimen 4H: embryonic day 10.5 (more )
Note: Double labeled: green - Sox2; red - Nedd9 (assay MGI:5428867).
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 4H

Specimen 5F: embryonic day 10.5 (more )
Note: Double labeled: green - Sox2; red - Nedd9 (assay MGI:5428867).
Structure Level Pattern Image Note
TS17: optic cup inner layer Present Regionally restricted 5F Expression was detected in the prospective retina in the area corresponding to the ventricular zone of the neuroepithelium.

Specimen 5G: embryonic day 10.5 (more )
Note: Double labeled: green - Sox2; red - Nedd9 (assay MGI:5428867).
Structure Level Pattern Image Note
TS17: nasal pit epithelium Present 5G Expression was detected in olfactory pit epithelium.

Specimen 7C: embryonic day 12.5 (more )
Note: Double labeled: green - Sox2; red - Nedd9 (assay MGI:5428867).
Structure Level Pattern Image Note
TS20: gut epithelium Present 7C Expression was detected in progenitors of the gut epithelium.

Specimen 7F: embryonic day 10.5 (more )
Note: Double labeled: green - Sox2; red - Nedd9 (assay MGI:5428867).
Structure Level Pattern Image Note
TS17: Rathke's pouch Present Scattered 7F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory