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Gene Expression Data
Assay Details
Assay
Reference: J:52602 Hunter PJ, et al., Mrj encodes a DnaJ-related co-chaperone that is essential for murine placental development. Development. 1999 Mar;126(6):1247-58
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5424562
Gene symbol: Dnajb6
Gene name: DnaJ heat shock protein family (Hsp40) member B6
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 7.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Structure Level Pattern Image Note
TS11: embryo Present 1A Expression is present in the egg cylinder.
Specimen 1B: embryonic day 8.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Structure Level Pattern Image Note
TS13: embryo Present Widespread 1B
Specimen 1C: embryonic day 12.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Structure Level Pattern Image Note
TS20: embryo Present Widespread 1C
TS20: neural retinal epithelium Strong 1C Expression is present in the ganglion neural layer.
Specimen 1D: embryonic day 15.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Note: This is a coronal section through the C6 certebra.
Structure Level Pattern Image Note
TS23: dorsal root ganglion Strong 1D
TS23: thymus primordium Strong 1D
Specimen 1G: embryonic day 15.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Note: This is a mid-sagittal section.
Structure Level Pattern Image Note
TS23: brain Present 1G
TS23: nasal cavity epithelium Present 1G
TS23: diencephalon Present 1G This is one of the brain regions with consistently higher levels of expression.
TS23: midbrain Present 1G This is one of the brain regions with consistently higher levels of expression.
TS23: trigeminal ganglion Present 1G This is one of the brain regions with consistently higher levels of expression.
Specimen Not shown: embryonic day 15.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Structure Level Pattern Image Note
TS23: testis Present
Specimen 3A: embryonic day 8.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Note: This tissue was bissected.
Structure Level Pattern Image Note
TS13: trophoblast giant cell Present 3A There is strong expression in the primary giant cells; expression in the secondary giant cells is weaker.
TS13: chorion Present Regionally restricted 3A Expression is present in the trophoblast cells.
TS13: ectoplacental cone Absent 3A
Specimen 3B: embryonic day 8.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Structure Level Pattern Image Note
TS13: chorion Present Regionally restricted 3B Expression is present in the trophoblast cells.
Specimen 3C,D: embryonic day 8.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Structure Level Pattern Image Note
TS13: chorion Present 3D , 3C Expression is present in the trophoblast cells, but expression is very low or undetectable in the mesothelium.
TS13: ectoplacental cone Absent 3C
TS13: allantois Ambiguous 3D , 3C Expression is very low or undetectable.
Specimen 3F: embryonic day 11.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Structure Level Pattern Image Note
TS19: trophoblast giant cell Present 3F
TS19: labyrinthine zone Present 3F Expression is present in the trophoblast component.
TS19: spongiotrophoblast Absent 3F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory