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Gene Expression Data
Assay Details
Assay
Reference: J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
Assay type: RNA in situ
MGI Accession ID: MGI:5421182
Gene symbol: Dkk3
Gene name: dickkopf WNT signaling pathway inhibitor 3
Probe: MH676 probe 567
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Cryosections of fresh frozen material were fixed in 4% paraformaldehyde for 20 min. before further processing. A tyramide-biotin/streptavidin amplification step was included in the in situ hybridization procedure. These data were downloaded from GenePaint.org on 1/30/12.
Results
Specimen MH676; Specimen C1277: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nervous system Strong Regionally restricted Embryo_C1277_5_2D
TS22: central nervous system Strong Regionally restricted Embryo_C1277_5_2D
TS22: telencephalon Strong Regionally restricted Embryo_C1277_5_2D
TS22: cerebral cortex Strong Regionally restricted Embryo_C1277_5_2D
TS22: neocortex Absent
TS22: olfactory cortex Absent
TS22: main olfactory bulb Absent
TS22: piriform cortex Absent
TS22: hippocampus Strong Regionally restricted Embryo_C1277_5_2D
TS22: basal ganglia Weak Regionally restricted Embryo_C1277_5_2A
TS22: corpus striatum Weak Regionally restricted Embryo_C1277_5_2A Expression was weak in the corpus striatum (lateral ganglionic eminence).
TS22: basal forebrain Absent
TS22: amygdala Absent
TS22: telencephalon septum Absent
TS22: pallidum Absent Expression was not detected in the pallidum (medial ganglionic eminence).
TS22: diencephalon Strong Regionally restricted Embryo_C1277_5_3D
TS22: thalamus Strong Regionally restricted Embryo_C1277_5_3D
TS22: hypothalamus Strong Regionally restricted Embryo_C1277_5_3D
TS22: midbrain Strong Regionally restricted Embryo_C1277_5_3C
TS22: pretectum Strong Regionally restricted Embryo_C1277_5_3C
TS22: superior colliculus Absent
TS22: inferior colliculus Absent
TS22: midbrain tegmentum Strong Regionally restricted Embryo_C1277_5_3D
TS22: hindbrain Strong Regionally restricted Embryo_C1277_5_2A
TS22: cerebellum Strong Regionally restricted Embryo_C1277_5_2A
TS22: pons Strong Regionally restricted Embryo_C1277_5_3D
TS22: medulla oblongata Strong Regionally restricted Embryo_C1277_5_3C
TS22: spinal cord Strong Regionally restricted Embryo_C1277_5_3B
TS22: choroid plexus Absent
TS22: meninges Absent
TS22: peripheral nervous system Absent
TS22: cranial ganglion Absent
TS22: dorsal root ganglion Absent
TS22: eye Strong Regionally restricted Embryo_C1277_5_1A
TS22: retina Strong Regionally restricted Embryo_C1277_5_1A
TS22: lens Moderate Ubiquitous Embryo_C1277_5_1A
TS22: nose Weak Regionally restricted Embryo_C1277_5_2B
TS22: olfactory epithelium Weak Regionally restricted Embryo_C1277_5_2B
TS22: ear Absent
TS22: inner ear Absent
TS22: cochlea Absent
TS22: inner ear labyrinth Absent
TS22: middle ear Absent
TS22: alimentary system Weak Regionally restricted Embryo_C1277_5_6C Expression was weak in the digestive system.
TS22: intestine Absent
TS22: salivary gland Absent
TS22: tongue Absent
TS22: tooth Absent
TS22: palatal shelf Absent
TS22: esophagus Absent
TS22: stomach Weak Regionally restricted Embryo_C1277_5_6C
TS22: liver Absent
TS22: respiratory system Absent
TS22: pharynx Absent
TS22: larynx Absent
TS22: trachea Absent
TS22: main bronchus Absent
TS22: lung Absent
TS22: urinary system Moderate Regionally restricted Embryo_C1277_5_3D Expression was detected in the genito-urinary system.
TS22: metanephros Absent
TS22: ureter Absent
TS22: bladder Moderate Regionally restricted Embryo_C1277_5_3D
TS22: urethra Absent
TS22: reproductive system Weak Regionally restricted Embryo_C1277_5_4B
TS22: genital tubercle Weak Regionally restricted Embryo_C1277_5_4B
TS22: gonad Absent
TS22: gland Weak Regionally restricted Embryo_C1277_5_5A Expression was weak in the endocrine system.
TS22: thyroid gland Absent
TS22: pituitary gland Absent
TS22: pancreas Absent
TS22: adrenal gland Weak Regionally restricted Embryo_C1277_5_5A
TS22: cardiovascular system Strong Regionally restricted Embryo_C1277_5_4A
TS22: heart Strong Regionally restricted Embryo_C1277_5_4A
TS22: heart atrium Strong Regionally restricted Embryo_C1277_5_4A
TS22: heart ventricle Strong Regionally restricted Embryo_C1277_5_4B
TS22: blood vessel Strong Regionally restricted Embryo_C1277_5_4A
TS22: hemolymphoid system Absent Expression was not detected in the immune system.
TS22: thymus primordium Absent
TS22: appendicular skeleton Moderate Regionally restricted Embryo_C1277_5_6D Expression was detected in the skeleton (limbs, shoulder, hip).
TS22: musculature Absent
TS22: face Weak Regionally restricted Embryo_C1277_5_4B Expression was weak in the face/soft tissues.
TS22: facial bone primordium Moderate Regionally restricted Embryo_C1277_5_3C
TS22: cranium Absent Expression was not detected in the skull (base and vault).
TS22: axial skeleton Moderate Regionally restricted Embryo_C1277_5_4D
TS22: tail Moderate Regionally restricted Embryo_C1277_5_3A
TS22: forelimb Moderate Regionally restricted Embryo_C1277_5_1A
TS22: hindlimb Moderate Regionally restricted Embryo_C1277_5_6D
TS22: integumental system Absent
TS22: skin Absent
TS22: hair Absent
TS22: vibrissa follicle Absent Expression was not detected in whisker follicle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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