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Gene Expression Data
Assay Details
Assay
Reference: J:179032 Sharlin DS, et al., Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea. Endocrinology. 2011 Dec;152(12):5053-64
Assay type: RNA in situ
MGI Accession ID: MGI:5308803
Gene symbol: Slc7a5
Gene name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
Probe: Lat1 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cochlear ganglion Weak 1A E18
TS26: cochlear duct Weak Regionally restricted 1A E18 Signals were detected in the spiral limbus, spiral ligament, and stria vascularis in a pattern indicative of sectioned blood vessels. Signal was also detected in spiral vessel, a blood vessel below the organ of Corti.

Specimen 1A P3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cochlear ganglion Present Regionally restricted 1A P3 Weaker signals were detected in nonvascular cell types in the spiral ganglion.
TS27: spiral ligament Present Regionally restricted 1A P3 Staining was in a pattern indicative of sectioned blood vessel.
TS27: spiral limbus Present Regionally restricted 1A P3 Staining was in a pattern indicative of sectioned blood vessel.
TS27: stria vascularis Present Regionally restricted 1A P3 Staining was in a pattern indicative of sectioned blood vessel.
TS27: organ of Corti Present Regionally restricted 1A P3 Weaker signals were detected in the greater and lesser epithelial ridges and hair cells of the organ of Corti.
TS27: spiral vessel Present 1A P3 Signal was detected in the spiral vessel, a blood vessel below the organ of Corti.

Specimen 1A P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cochlear ganglion Present 1A P5
TS28: spiral ligament Present 1A P5
TS28: spiral limbus Present 1A P5
TS28: stria vascularis Present Regionally restricted 1A P5 Staining was in a pattern indicative of sectioned blood vessels.
TS28: spiral vessel Present 1A P5 Signal was detected in the spiral vessel, a blood vessel below the organ of Corti.

Specimen 1A P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cochlear ganglion Present Regionally restricted 1A P7 Staining was in a pattern indicative of sectioned blood vessel.
TS28: spiral ligament Present Regionally restricted 1A P7 Staining was in a pattern indicative of sectioned blood vessel.
TS28: spiral limbus Present Regionally restricted 1A P7 Staining was in a pattern indicative of sectioned blood vessel.
TS28: stria vascularis Present Regionally restricted 1A P7 Staining was in a pattern indicative of sectioned blood vessel.
TS28: spiral vessel Present 1A P7

Specimen 1A P10: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cochlear ganglion Present Regionally restricted 1A P10 Staining was in a pattern indicative of sectioned blood vessel. Expression signals decreased after P7.
TS28: spiral ligament Present Regionally restricted 1A P10 Staining was in a pattern indicative of sectioned blood vessel. Expression signals decreased after P7.
TS28: spiral limbus Present Regionally restricted 1A P10 Staining was in a pattern indicative of sectioned blood vessel. Expression signals decreased after P7.
TS28: stria vascularis Present Regionally restricted 1A P10 Staining was in a pattern indicative of sectioned blood vessel. Expression signals decreased after P7.
TS28: spiral vessel Present 1A P10 Expression signals decreased after P7.

Specimen 3A: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: stria vascularis Present Regionally restricted 3A Signal in the intermediate region of stria vascularis.
TS28: spiral ligament Present Regionally restricted 3A Signals in blood vessel-like structures in the spiral ligament.

Specimen 3C: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 3C Signals were transiently detected in inner and outer hair cells and more weakly in Deiters support cells residing below the outer hair cells.
TS27: cochlear duct Present Regionally restricted 3C Signal was detected in the spiral vessel.

Specimen 3E: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cochlear ganglion Present Regionally restricted 3E Signals were in vessel-like structures and weakly in cell bodies of neurons.
TS27: blood vessel Present Regionally restricted 3E Signal was detected in bood vessels of the spiral ganglion.

Specimen 3G: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: organ of Corti Absent 3G Signal was not detected in hair cells.
TS28: spiral vessel Present 3G

Specimen 6A Tshr+/+: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cochlea Present 6A +/+

Specimen 6A Tsgr-/-: postnatal day 7; Tshrtm1Rmar/Tshrtm1Rmar (more )
Structure Level Pattern Image Note
TS28: cochlea Present 6A Tshr-/- Expression was unchanged in mutant mice compared with wild type.

Specimen S1A Lat1: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cochlea Present S1A Lat1


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory