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Gene Expression Data
Assay Details
Assay
Reference: J:178893 Sivakamasundari V, et al., New Bapx1(Cre-EGFP) mouse lines for lineage tracing and conditional knockout studies. Genesis. 2012 Apr;50(4):375-83
Assay type: Recombinase reporter
MGI Accession ID: MGI:5308266
Gene symbol: Nkx3-2
Gene name: NK3 homeobox 2
Reporter: lacZ
Direct Detection
Results
Specimen Fig. 2A c: embryonic day 9.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx3-2tm4.1(cre)Tlu/Nkx3-2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: head mesenchyme Present 2A_c Staining is observed in the cephalic mesenchyme.
TS15: mesenchyme derived from splanchnopleure Present 2A_c Staining is observed in the splanchnic mesenchyme.
TS15: somite Present 2A_c Staining is observed in the somites.
Specimen Fig. 2A f: embryonic day 10.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx3-2tm4.1(cre)Tlu/Nkx3-2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: head mesenchyme Present 2A_f
TS17: sclerotome Present 2A_f
TS17: trunk mesenchyme Present 2A_f
TS17: 1st branchial arch Weak 2A_f Staining is observed around the first branchial arch.
Specimen Fig. 2A i: embryonic day 11.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx3-2tm4.1(cre)Tlu/Nkx3-2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 2A_i
TS19: vertebral pre-cartilage condensation Present 2A_i
TS19: 1st branchial arch Present 2A_i Staining is stronger in the first arch than that observed at E10.5.
Specimen Fig. 2A l: embryonic day 12.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx3-2tm4.1(cre)Tlu/Nkx3-2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: Meckel's cartilage Present 2A_l Staining is observed in a domain adjoining Meckel's cartilage.
TS20: rib pre-cartilage condensation Present 2A_l Staining persists in the cartilage condensations of the ribs.
TS20: forelimb pre-cartilage condensation Present 2A_l Staining persists in the cartilage condensations of the forelimbs.
TS20: vertebral cartilage condensation Present 2A_l Staining persists in the cartilage condensations of the vertebra.
TS20: hindlimb pre-cartilage condensation Present 2A_l Staining is observed in the hindlimbs for the first time.
Specimen Fig. 2A o: embryonic day 13.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx3-2tm4.1(cre)Tlu/Nkx3-2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: forelimb pre-cartilage condensation Present 2A_o
TS21: limb pre-cartilage condensation Present 2A_o
TS21: vertebral cartilage condensation Present 2A_o
TS21: rib pre-cartilage condensation Present 2A_o
Specimen Fig. 3c: embryonic day 11.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx3-2tm4.1(cre)Tlu/Nkx3-2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: vertebral pre-cartilage condensation Present 3c Staining is observed in the condensing mesenchymal prevertebrae.
TS19: neural tube Absent 3c No staining is observed in neural tube tissue adjacent to the condensing vertebrae.
Specimen Fig. 3f: embryonic day 12.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx3-2tm4.1(cre)Tlu/Nkx3-2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: intestine mesenchyme Present 3f Staining is observed in the intestinal mesoderm.
TS20: intestine epithelium Absent 3f No staining is observed in the endodermal epithelium.
Specimen Fig. 3i: embryonic day 12.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Nkx3-2tm4.1(cre)Tlu/Nkx3-2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: forelimb pre-cartilage condensation Present 3i , 3l Staining is observed in the cartilage condensation of the limbs.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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