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Gene Expression Data
Assay Details
Assay
Reference: J:70272 Kibar Z, et al., Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. Nat Genet. 2001 Jul;28(3):251-5
Assay type: RNA in situ
MGI Accession ID: MGI:5302816
Gene symbol: Vangl2
Gene name: VANGL planar cell polarity 2
Probe: Ltap cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4a: embryonic day 7.0-7.5 (more )
Structure Level Pattern Image Note
TS10: neural ectoderm Strong 4a
Specimen 4b: embryonic day 7.5-8.0 (more )
Structure Level Pattern Image Note
TS11: neural ectoderm Strong 4b
Specimen 4c: embryonic day 7.5-8.0 (more )
Structure Level Pattern Image Note
TS11: neural ectoderm Strong 4c
Specimen 4d: embryonic day 7.5-8.0 (more )
Structure Level Pattern Image Note
TS11: future brain neural fold Present Regionally restricted 4d Absent in the floor plate.
Specimen 4e: embryonic day 7.5-8.0 (more )
Structure Level Pattern Image Note
TS11: embryo mesoderm Present Regionally restricted 4e Expression is in the mesoderm subjacent to the caudal neural plate.
TS11: future spinal cord neural plate Present Regionally restricted 4e Absent in the floor plate.
TS11: notochordal plate Absent 4e
Specimen 4f: embryonic day 8.0-8.5 (more )
Structure Level Pattern Image Note
TS12: neural ectoderm Present Regionally restricted 4f
TS12: embryo Present Regionally restricted 4f Expression is in a cluster of cells at the base of the allantois.
TS12: notochord Absent 4f
Specimen 4g: embryonic day 8.0-8.5 (more )
Note: Double labeled: purple - Vangl2 (Ltap); orange/red - Egr2 (Krox20; assay MGI:5304177).
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 4g Absent in rhombomere 3 and 5.
Specimen 4h: embryonic day 8.0-8.5 (more )
Structure Level Pattern Image Note
TS12: future hindbrain Present 4h
TS12: future hindbrain floor plate Absent 4h
Specimen 4i: embryonic day 8.0-8.5 (more )
Structure Level Pattern Image Note
TS12: hindgut diverticulum Present 4i
TS12: future spinal cord neural plate Present Regionally restricted 4i Expression is in the lateral edges.
Specimen 5a: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: hindgut diverticulum Present 5a
TS13: neural ectoderm Present 5a
TS13: embryo Present Regionally restricted 5a Expression is in a cluster of cells at the base of the allantois.
Specimen 5b: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: hindgut diverticulum Present 5b
TS14: nervous system Present 5b
TS14: embryo Present Regionally restricted 5b Expression is in a cluster of cells at the base of the allantois.
Specimen 5c: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: hindgut diverticulum Present 5c
TS14: neural tube Present 5c
TS14: neural tube floor plate Weak 5c
TS14: notochord Absent 5c
TS14: somite Absent 5c
Specimen 5d: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: future spinal cord neural plate Present 5d
TS14: hindgut diverticulum Present 5d
TS14: future spinal cord neural fold Present Regionally restricted 5d Absent in the lateral edges.
TS14: gut Present Regionally restricted 5d Expression is throughout most of the circumference of the gut, and is strongest at the lateral edges.
TS14: somite Absent 5d
Specimen 5e: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: nervous system Present 5e
TS15: otocyst Present 5e
Specimen 5f: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: nervous system Present 5f
TS16: otocyst Present 5f
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory