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Gene Expression Data
Assay Details
Assay
Reference: J:81583 Abu-Abed S, et al., Developing with lethal RA levels: genetic ablation of Rarg can restore the viability of mice lacking Cyp26a1. Development. 2003 Apr;130(7):1449-59
Assay type: RNA in situ
MGI Accession ID: MGI:5301587
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe43
Probe preparation: RNA
Results
Specimen 5A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component Present 5A Normal expression in the midbrain-hindbrain junction, maxillary and mandibular components of the first branchial arch, otic vesicle, heart and associated vasculature, hindgut endoderm, and tail bud nascent mesoderm and neuroepithelium.
TS15: 1st branchial arch maxillary component Present 5A Normal expression in the midbrain-hindbrain junction, maxillary and mandibular components of the first branchial arch, otic vesicle, heart and associated vasculature, hindgut endoderm, and tail bud nascent mesoderm and neuroepithelium.
TS15: blood vessel Present 5A Normal expression in the midbrain-hindbrain junction, maxillary and mandibular components of the first branchial arch, otic vesicle, heart and associated vasculature, hindgut endoderm, and tail bud nascent mesoderm and neuroepithelium.
TS15: heart Present 5A Normal expression in the midbrain-hindbrain junction, maxillary and mandibular components of the first branchial arch, otic vesicle, heart and associated vasculature, hindgut endoderm, and tail bud nascent mesoderm and neuroepithelium.
TS15: hindgut epithelium Present 5A Normal expression in the midbrain-hindbrain junction, maxillary and mandibular components of the first branchial arch, otic vesicle, heart and associated vasculature, hindgut endoderm, and tail bud nascent mesoderm and neuroepithelium.
TS15: midbrain-hindbrain junction Present 5A Normal expression in the midbrain-hindbrain junction, maxillary and mandibular components of the first branchial arch, otic vesicle, heart and associated vasculature, hindgut endoderm, and tail bud nascent mesoderm and neuroepithelium.
TS15: otocyst Present 5A Normal expression in the midbrain-hindbrain junction, maxillary and mandibular components of the first branchial arch, otic vesicle, heart and associated vasculature, hindgut endoderm, and tail bud nascent mesoderm and neuroepithelium.
TS15: tail mesenchyme Present 5A Normal expression in the midbrain-hindbrain junction, maxillary and mandibular components of the first branchial arch, otic vesicle, heart and associated vasculature, hindgut endoderm, and tail bud nascent mesoderm and neuroepithelium.
TS15: tail nervous system Present 5A Normal expression in the midbrain-hindbrain junction, maxillary and mandibular components of the first branchial arch, otic vesicle, heart and associated vasculature, hindgut endoderm, and tail bud nascent mesoderm and neuroepithelium.
TS15: future brain Present Regionally restricted 5A Authors report expression in the commissural plate.

Specimen 5B: embryonic day 9.5; Cyp26a1tm1.1Ptk/Cyp26a1tm1.1Ptk (more )
Structure Level Pattern Image Note
TS15: hindgut Present Regionally restricted 5B Expression in hindgut stops at the level of the posterior neuropore.
TS15: tail Trace 5B Expression virtually absent in the tailbud.

Specimen 5B inset: embryonic day 9.5; Cyp26a1tm1.1Ptk/Cyp26a1tm1.1Ptk (more )
Structure Level Pattern Image Note
TS15: tail mesenchyme Weak 5B inset Expression is down-regulated in the nascent mesoderm of tail bud tissues.

Specimen not shown: embryonic day 9.5; Cyp26a1tm1.1Ptk/Cyp26a1tm1.1Ptk, Rargtm1Ipc/Rarg+ (more )
Structure Level Pattern Image Note
TS15: tail Trace Expression virtually absent in the tailbud.

Specimen 5C: embryonic day 9.5; Cyp26a1tm1.1Ptk/Cyp26a1tm1.1Ptk, Rargtm1Ipc/Rargtm1Ipc (more )
Structure Level Pattern Image Note
TS15: embryo Present Regionally restricted 5C Authors report patterns of expression comparable with that of wild-type embryos.
TS15: 1st branchial arch mandibular component Present 5C
TS15: 1st branchial arch maxillary component Present 5C
TS15: otocyst Present 5C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory