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Gene Expression Data
Assay Details
Assay
Reference: J:166449 Nishino J, et al., Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J Neurosci. 2010 Nov 10;30(45):15228-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5301085
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tubulin beta 3 (clone TUJ1, MMS-435P/801202)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 5C upper left: embryonic day 10.5 (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (BFABP; assay MGI:5301084).
Structure Level Pattern Image Note
TS17: enteric nervous system Present Regionally restricted 5C upper left Expressed in neurons in the foregut and midgut.

Specimen 5C upper right: embryonic day 10.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (BFABP; assay MGI:5301084).
Structure Level Pattern Image Note
TS17: enteric nervous system Present Regionally restricted 5C upper right Expressed in neurons in the foregut and midgut. Normal expression relative to controls.

Specimen 5C lower left: embryonic day 18.5 (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (BFABP; assay MGI:5301084).
Structure Level Pattern Image Note
TS26: enteric nervous system Present Regionally restricted 5C lower left Expressed in neurons in the foregut, midgut and hindgut.

Specimen 5C lower right: embryonic day 18.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (BFABP; assay MGI:5301084).
Structure Level Pattern Image Note
TS26: enteric nervous system Present Regionally restricted 5C lower right Expressed in neurons in the foregut, midgut and hindgut. Normal expression in the foregut, midgut and hindgut relative to controls.

Specimen 5G upper left: embryonic day 10.5 (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (BFABP; assay MGI:5301084).
Structure Level Pattern Image Note
TS17: sympathetic nervous system Present Regionally restricted 5G upper left Expressed in neurons in sympathetic ganglia.

Specimen 5G upper right: embryonic day 10.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (BFABP; assay MGI:5301084).
Structure Level Pattern Image Note
TS17: sympathetic nervous system Present Regionally restricted 5G upper right Expressed in neurons in sympathetic ganglia. Normal expression in the sympathetic ganglia relative to controls.

Specimen 5G lower left: embryonic day 18.5 (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (BFABP; assay MGI:5301084).
Structure Level Pattern Image Note
TS26: sympathetic ganglion Present Regionally restricted 5G lower left Expressed in neurons.

Specimen 5G lower right: embryonic day 18.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (BFABP; assay MGI:5301084).
Structure Level Pattern Image Note
TS26: sympathetic ganglion Present Regionally restricted 5G lower right Expressed in neurons. Normal expression relative to controls.

Specimen not shown - +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present Regionally restricted Expressed in neurons.

Specimen not shown - lacZ/lacZ: embryonic day 10.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present Regionally restricted Expressed in neurons. Normal expression relative to controls.

Specimen not shown - +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: dorsal root ganglion Present Regionally restricted Expressed in neurons.

Specimen not shown - lacZ/lacZ: embryonic day 18.5; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Structure Level Pattern Image Note
TS26: dorsal root ganglion Present Regionally restricted Expressed in neurons. Normal expression relative to controls.

Specimen 6B - +/+: postnatal day 0 (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (BFABP; assay MGI:5301084).
Structure Level Pattern Image Note
TS27: myenteric nerve plexus Present Regionally restricted 6B bottom left Expressed in neurons.

Specimen 6B - lacZ/lacZ: postnatal day 0; Lgi4tm1Sjm/Lgi4tm1Sjm (more )
Note: Double labeled: red - Tubb3; green - Fabp7 (BFABP; assay MGI:5301084).
Structure Level Pattern Image Note
TS27: myenteric nerve plexus Present Regionally restricted 6B bottom right Expressed in neurons. Relatively normal expression compared with controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory