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Gene Expression Data
Assay Details
Assay
Reference: J:86049 Gavalas A, et al., Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes. Development. 2003 Dec;130(23):5663-79
Assay type: RNA in situ
MGI Accession ID: MGI:5300168
Gene symbol: Gata2
Gene name: GATA binding protein 2
Probe: Gata2 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2M: embryonic day 10.5 (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS17: hindbrain Present 2M
TS17: rhombomere 4 Strong Regionally restricted 2M Expression is present in ventral rhombomere 4.
Specimen 2N: embryonic day 10.5; Hoxb1tm1Brd/Hoxb1tm1Brd (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS17: hindbrain Present 2N
TS17: rhombomere 4 Present 2N Expression is present in rhombomere 4, but unlike in wild-type, is absent in the ventral domain.
Specimen 2O: embryonic day 10.5; Hoxb2tm1Fmr/Hoxb2tm1Fmr (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS17: hindbrain Present 2O
TS17: rhombomere 4 Present 2O Expression is present in ventral rhombomere 4, but the domain is slightly reduced in the mutant compared to wild type.
Specimen 2P: embryonic day 10.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc (more )
Note: This specimen is flat-mounted.
Structure Level Pattern Image Note
TS17: hindbrain Present 2P
TS17: rhombomere 4 Present 2P The width and the strength of the ventral rhombomere 4 expression domain are greatly reduced in the mutant relative to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory