About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:88447 Solecki DJ, et al., Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation. Neuron. 2001 Aug 30;31(4):557-68
Assay type: RNA in situ
MGI Accession ID: MGI:5294330
Gene symbol: Notch2
Gene name: notch 2
Probe: Notch2 cDNA7
Probe preparation: Antisense RNA
Results
Specimen 2A: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cerebellum Present 2A Low-level expression in the cerebellar anlage.
TS24: 4th ventricle choroid plexus Strong 2A
TS24: lateral ventricle choroid plexus Strong 2A

Specimen 2B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebellum Purkinje cell layer Present 2B
TS27: cerebellum external granule cell layer Present 2B

Specimen 2C/E: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong Non-Uniform 2C , 2E Expression in the proliferating granule neuron precursors, and is downregulated in differentiating granule neurons in deeper inner layer.
TS28: cerebellum Purkinje cell layer Present Regionally restricted 2C , 2E Expression in a subpopulation of cells in the layer, probably Bergman glia.
TS28: cerebellum molecular layer Absent 2E , 2C Expression was not detected in migrating granule neurons.
TS28: cerebellum internal granule cell layer Absent 2C , 2E Expression was not detected in the differentiated neurons.

Specimen 2D: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 2D Expression was reduced in the cerebellum.

Specimen not shown: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: cerebellum Absent

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/28/2026
MGI 6.24
The Jackson Laboratory