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Gene Expression Data
Assay Details
Assay
Reference: J:51995 Hermey G, et al., Identification of a novel seven-transmembrane receptor with homology to glycoprotein receptors and its expression in the adult and developing mouse. Biochem Biophys Res Commun. 1999 Jan 8;254(1):273-9
Assay type: RNA in situ
MGI Accession ID: MGI:5292028
Gene symbol: Lgr5
Gene name: leucine rich repeat containing G protein coupled receptor 5
Probe: Fex cDNA2
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 3A, A': postnatal adult (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS28: ovary mature follicle Present 3A , 3A'
TS28: ovary primary follicle Absent 3A , 3A'
TS28: ovary secondary follicle Absent 3A , 3A'
Specimen 4A, A': postnatal adult (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS28: adrenal medulla Present 4A , 4A' Expression is in chromaffin cells.
TS28: adrenal cortex Absent 4A , 4A'
Specimen 4B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: adrenal medulla Present 4B Expression is in chromaffin cells.
TS28: adrenal cortex Absent 4B
Specimen 5A,A': embryonic day 8.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS13: ectoplacental cone Present Single cells 5A , 5A'
Specimen 5B,B': embryonic day 9.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS28: placenta Strong 5B , 5B' Expression is in the labyrinthine region of the forming placenta.
TS15: embryo Weak 5B , 5B'
Specimen 6A,A',B,B': embryonic day 10.5 (more )
Note: (B, B') Magnification of the area framed in (A, A'). Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS17: midbrain roof plate Strong 6A' , 6A , 6B , 6B'
TS17: fronto-nasal process Present 6A' , 6A
TS17: optic cup Present 6A' , 6A
TS17: future spinal cord Present Regionally restricted 6A' , 6A Expression is in the ventral and dorsal spinal cord.
TS17: gonad primordium Absent 6A' , 6A
Specimen 7C,C': embryonic day 11.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 7C , 7C' Expression is in the neuroepithelium lining the 4th ventricle.
TS19: midbrain-hindbrain junction Present Regionally restricted 7C , 7C' Expression is in the neuroepithelium lining the 4th ventricle.
TS19: future spinal cord Present Regionally restricted 7C' , 7C Expression is in the dorsal and ventral areas.
TS19: eye Present Regionally restricted 7C' , 7C Expression is in the optic cup.
TS19: mandibular process mesenchyme Present Regionally restricted 7C , 7C' Expression is in the mesenchyme surrounding the mandibular cleft.
TS19: somite Present Regionally restricted 7C , 7C' Expression is in condensing mesenchyme.
TS19: diencephalon Absent 7C , 7C'
TS19: gonad Absent 7C , 7C'
Specimen 8A,A': embryonic day 11.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS19: future spinal cord Present 8A' , 8A Expression is in the ventral and dorsal area extending laterally from the neuroepithelium lining the neural canal.
Specimen 8B,B': embryonic day 11.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS19: future spinal cord Present 8B' , 8B
TS19: axial skeleton Present Regionally restricted 8B' , 8B Expression is in the condensing mesenchyme of the intervertebrate disc anlagen.
Specimen 8C,C': embryonic day 11.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS19: neural retinal epithelium Present 8C , 8C'
TS19: hindbrain Present Regionally restricted 8C' , 8C Expression is in the neuroepithelium lining the 4th ventricle.
TS19: lens vesicle Absent 8C' , 8C
Specimen 9A,A',B,B': embryonic day 13.5 (more )
Note: (B, B') A magnification of the facial region of the embryo shown in (A, A'). Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS21: diencephalon Strong Regionally restricted 9A , 9A' Expression is at the border between di- and mesencephalon.
TS21: midbrain Strong Regionally restricted 9A , 9A' Expression is at the border between di- and mesencephalon.
TS21: lower jaw epithelium Present Regionally restricted 9A' , 9A Expression is in the mesenchyme and epithelium surrounding the mandibular cleft.
TS21: lower jaw mesenchyme Present Regionally restricted 9A' , 9A Expression is in the mesenchyme and epithelium surrounding the mandibular cleft.
TS21: axial skeleton Present Regionally restricted 9A' , 9A Expression is in the intervertebral discs.
TS21: tooth Present Regionally restricted 9B , 9B' , 9A , 9A' Expression is in the condensed mesenchyme and the ameloblast of the tooth anlage.
TS21: mandible mesenchyme Present 9B , 9A , 9A' , 9B'
TS21: tongue epithelium Present 9B , 9A , 9A' , 9B'
TS21: medulla oblongata Weak Regionally restricted 9A , 9A' Expression is at the border.
TS21: metencephalon Weak Regionally restricted 9A , 9A' Expression is at the border.
TS21: gonad Absent 9A , 9A'
Specimen 9C,C': embryonic day 13.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS21: neural retinal epithelium Present 9C , 9C'
TS21: pituitary gland Present 9C , 9C'
TS21: primary palate mesenchyme Present 9C , 9C'
TS21: nose Present Regionally restricted 9C' , 9C Expression is in the mesenchyme lining the olfactory epithelium.
Specimen 9D,D': embryonic day 13.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS21: viscerocranium Present Regionally restricted 9D' , 9D Expression is in epithelia and mesenchymal tissues under the parachordal plate.
TS21: pulmonary artery Present 9D' , 9D
TS21: trunk mesenchyme Weak Regionally restricted 9D , 9D' Body wall and mesenchyme surrounding internal organs, e.g., the capsule of the liver.
Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nervous system Trace
TS22: gonad Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory