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Gene Expression Data
Assay Details
Assay
Reference: J:60832 Pattyn A, et al., Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b. Development. 2000 Apr;127(7):1349-58
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5141496
Gene symbol: Phox2b
Gene name: paired-like homeobox 2b
Reporter: lacZ
Antibody: anti-B-galactosidase (Rockland)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 3B: embryonic day 10.5; Phox2btm1Jbr/Phox2b+ (more )
Note: Double labeled: green - Phox2b; red - Tubb3 (assay MGI:2149611).
Structure Level Pattern Image Note
TS17: rhombomere 4 Present Regionally restricted 3B Expression is present in the ventral region.
Specimen 3B': embryonic day 10.5; Phox2btm1Jbr/Phox2btm1Jbr (more )
Note: Double labeled: green - Phox2b; red - Tubb3 (assay MGI:2149611).
Structure Level Pattern Image Note
TS17: rhombomere 4 Present 3B' Expression is present in the ventral region. However, in the mutant these cells are not differentiating into postmitotic neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory