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Gene Expression Data
Assay Details
Assay
Reference: J:57890 Gerard M, et al., Disruption of the mouse necdin gene results in early post-natal lethality [see comments]. Nat Genet. 1999 Oct;23(2):199-202
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5140733
Gene symbol: Ndn
Gene name: necdin, MAGE family member
Reporter: lacZ
Direct Detection
Results
Specimen Not shown (paternal allele): embryonic day 12.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Staining for the paternally inherited allele is predominantly found in the central nervous system.

Specimen Not shown (paternal allele): embryonic day 14.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS22: central nervous system Present Staining for the paternally inherited allele is predominantly found in the central nervous system.

Specimen 3a (paternal allele): embryonic day 17.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS25: brain Present 3a upper Expression is seen when the allele is paternally inherited.

Specimen 3b: embryonic day 16.0; Ndntm2Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS24: hypothalamus Present 3b This is the tissue with the highest level of expression when the allele is paternally inherited.
TS24: brain Present 3b Expression is present in most areas of the brain when the allele is paternally inherited.
TS24: brown fat Present 3b
TS24: cartilage Present 3b
TS24: dorsal root ganglion Present 3b
TS24: medulla oblongata Present 3b
TS24: pons Present 3b
TS24: spinal cord Present 3b
TS24: tongue Present 3b
TS24: heart Trace 3b
TS24: lung Trace 3b

Specimen 3c: embryonic day 16.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS24: central nervous system Present 3c Staining for the paternally inherited allele is predominantly found in the central nervous system.
TS24: hypothalamus Present 3c

Specimen Not shown (paternal allele): embryonic day 18.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS26: central nervous system Present Staining for the paternally inherited allele is predominantly found in the central nervous system.

Specimen Not shown (paternal allele): embryonic day 19.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS26: central nervous system Present Staining for the paternally inherited allele is predominantly found in the central nervous system.

Specimen Not shown (paternal allele): postnatal newborn; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS27: central nervous system Present Staining for the paternally inherited allele is predominantly found in the central nervous system.

Specimen Not shown (materal allele): embryonic day 12.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS20: embryo Absent No expression is seen when the allele is maternally inherited.

Specimen Not shown (materal allele): embryonic day 14.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS22: embryo Absent No expression is seen when the allele is maternally inherited.

Specimen Not shown (materal allele): embryonic day 16.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS24: embryo Absent No expression is seen when the allele is maternally inherited.

Specimen 3A (materal allele): embryonic day 17.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS25: brain Absent 3a lower No expression is seen when the allele is maternally inherited.

Specimen Not shown (materal allele): embryonic day 18.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS26: embryo Absent No expression is seen when the allele is maternally inherited.

Specimen Not shown (materal allele): embryonic day 19.0; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS26: embryo Absent No expression is seen when the allele is maternally inherited.

Specimen Not shown (materal allele): postnatal newborn; Ndntm1Stw/Ndn+ (more )
Structure Level Pattern Image Note
TS27: mouse Absent No expression is seen when the allele is maternally inherited.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory