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Gene Expression Data
Assay Details
Assay
Reference: J:55841 Hamada Y, et al., Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development. 1999 Aug;126(15):3415-24
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5140409
Gene symbol: Notch2
Gene name: notch 2
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 8.5; Notch2tm1Yha/Notch2+ (more )
Structure Level Pattern Image Note
TS13: allantois Strong 2A
TS13: primitive streak Strong 2A
TS13: somite Strong Non-Uniform 2A The strongest signals are seen in the most recently formed somites, then gradually lessens toward the more rostral, older ones.
TS13: neural plate Strong Regionally restricted 2A Expression is present in the ventral-most cells of the neural groove.
Specimen Not shown: embryonic day 9.0; Notch2tm1Yha/Notch2+ (more )
Structure Level Pattern Image Note
TS14: somite Present Non-Uniform The strongest signals are seen in the most recently formed somites, then gradually lessens toward the more rostral, older ones.
TS14: floor plate Present
Specimen 2B: embryonic day 9.5; Notch2tm1Yha/Notch2+ (more )
Structure Level Pattern Image Note
TS15: future brain floor plate Strong 2B
TS15: future brain roof plate Strong 2B
TS15: neural tube floor plate Strong 2B
TS15: neural tube roof plate Strong 2B
TS15: somite Strong 2B
TS15: future brain Present Regionally restricted 2B Expression is present in the neuroepithelium.
TS15: optic vesicle Present Regionally restricted 2B Expression is present in the neuroepithelium.
TS15: otocyst Present Regionally restricted 2B Expression is present in the neuroepithelium.
TS15: heart Absent 2B
Specimen 2D-left: embryonic day 10.5; Notch2tm1Yha/Notch2+ (more )
Structure Level Pattern Image Note
TS17: branchial arch Present 2D left
TS17: limb Present 2D left
TS17: midbrain roof plate Present 2D left
TS17: somite Present 2D left
Specimen 2D-right: embryonic day 10.5; Notch2tm1Yha/Notch2tm1Yha (more )
Structure Level Pattern Image Note
TS17: midbrain roof plate Present 2D right Expression is pronounced.
TS17: branchial arch Present 2D right
TS17: limb Present 2D right
TS17: somite Present 2D right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory