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Gene Expression Data
Assay Details
Assay
Reference: J:48521 Jiang R, et al., The Slug gene is not essential for mesoderm or neural crest development in mice. Dev Biol. 1998 Jun 15;198(2):277-85
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5014360
Gene symbol: Snai2
Gene name: snail family zinc finger 2
Reporter: lacZ
Direct Detection
Results
Specimen 3A: embryonic day 8.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS13: migrating neural crest Present 3A Expression in migratory cephalic neural crest cells at the level of the midbrain and hindbrain.
TS13: trunk somite Present 3A Expression was transiently detected in newly formed somites.
TS13: allantois Present Regionally restricted 3A Expression in the mesoderm.
TS13: yolk sac Present Regionally restricted 3A Expression in the mesoderm.
Specimen 3C: embryonic day 9.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted 3C Expression in the rostral half of each somite.
TS15: extraembryonic component Present 3C
Specimen 3E: embryonic day 8.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS13: trunk mesenchyme derived from neural crest Present 3E
TS13: future spinal cord neural crest Absent 3E No expression was detected in premigratory neural crest cells along the dorsal midline.
Specimen 4A: embryonic day 7.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS11: yolk sac mesoderm Present 4A
TS11: amnion Present Regionally restricted 4A Expression in the mesoderm layer of the amnion.
TS11: embryo Absent 4A
Specimen 4B: embryonic day 7.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS11: yolk sac mesoderm Present 4B
TS11: amnion Present Regionally restricted 4B Expression in the mesoderm layer of the amnion.
TS11: embryo Absent 4B
Specimen 4C: embryonic day 9.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS15: trunk mesenchyme Present Regionally restricted 4C Expression in the lateral mesoderm.
Specimen 4D: embryonic day 9.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS15: trunk mesenchyme derived from neural crest Present Regionally restricted 4D Expression in cells migrating through the rostral half of each somite.
Specimen 4E: embryonic day 10.0-10.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch mandibular component mesenchyme derived from neural crest Present 4E
TS16: 1st branchial arch maxillary component mesenchyme derived from neural crest Present 4E
TS16: eye mesenchyme Present 4E Expression in periocular mesenchyme.
Specimen 4F: embryonic day 10.0-10.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS16: lens pit Present 4F
TS16: head mesenchyme Present Regionally restricted 4F Expression in periocular mesenchyme, the lens vesicle and lens epithelium.
TS16: optic cup outer layer Absent 4F No expression in developing retina.
Specimen 5A: embryonic day 10.0-10.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS16: limb ectoderm Present Regionally restricted 5A Expression is observed in the ventral region.
TS16: limb mesenchyme Present Regionally restricted 5A Expression is observed in the ventral region.
Specimen 5B: embryonic day 10.0-10.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS16: limb ectoderm Present Regionally restricted 5B Expression is observed in the ventral region.
TS16: limb mesenchyme Present Regionally restricted 5B Expression is observed in the ventral region.
TS16: trunk Present 5B Expression in several mesodermally derived tissues.
Specimen 5C: embryonic day 10.0-10.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS16: limb ectoderm Present 5C
TS16: limb mesenchyme Present Graded 5C Expression is highest in the anterior region of the limb mesenchyme, with weaker expression in the posterior mesenchyme.
Specimen 5D: embryonic day 10.0-10.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS16: limb mesenchyme Present Graded 5D Expression is highest in the anterior region of the limb mesenchyme, with weaker expression in the posterior mesenchyme.
TS16: limb ectoderm Present 5D
Specimen 5E: embryonic day 11.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS19: limb Present 5E
Specimen not shown: embryonic day 9.5; Snai2tm1Grid/Snai2+ (more )
Structure Level Pattern Image Note
TS15: head mesenchyme derived from neural crest Present Regionally restricted Expression in cephalic neural crest.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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