Nme2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:105464 Amrein L, et al., Expression patterns of nm23 genes during mouse organogenesis. Cell Tissue Res. 2005 Dec;322(3):365-78
Assay type:	RNA in situ
MGI Accession ID:	MGI:4949067
Gene symbol:	Nme2
Gene name:	NME/NM23 nucleoside diphosphate kinase 2

Probe:	nm23-M2 i
Probe preparation:	labelled with S35
Visualized with:	Autoradiography
Assay notes:	Two oligonucleotide probes were described for this gene (see probe records MGI:4948917 and MGI:4948918 for the sequences). Authors indicate that one or both were used in this RNA in situ hybridization assay.

Results

Specimen 3b: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: embryo	Present	Widespread	3b
TS21: dorsal root ganglion	Strong		3b

Specimen Table 1 E13.5: embryonic day 13.5 (more

)

Specimen Table 1 E15.5: embryonic day 15.5 (more

)

Structure	Level	Pattern	Note
TS23: main olfactory bulb	Present	Regionally restricted	Expression was abundant in the granular cell layer and moderate in the subependymal zone.
TS23: cerebellum	Strong
TS23: cerebral cortex ventricular layer	Strong
TS23: cortical plate	Strong
TS23: dorsal root ganglion	Strong
TS23: hair follicle	Strong
TS23: intestine	Strong
TS23: lung	Strong
TS23: midbrain	Strong
TS23: spinal cord	Strong
TS23: tongue	Strong
TS23: trigeminal ganglion	Strong
TS23: eye	Moderate
TS23: heart	Moderate
TS23: thymus primordium	Weak

Specimen Table 1 E18.5: embryonic day 18.5 (more

)

Structure	Level	Pattern	Note
TS26: main olfactory bulb	Present	Regionally restricted	Expression was abundant in the granular cell layer and moderate in the subependymal zone.
TS26: cerebellum	Present	Regionally restricted	Expression was moderate in the external granular layer and abundant in the internal granular layer.
TS26: cortical plate	Strong
TS26: dorsal root ganglion	Strong
TS26: hair follicle	Strong
TS26: heart	Strong
TS26: intestine	Strong
TS26: midbrain	Strong
TS26: spinal cord	Strong
TS26: thymus	Strong
TS26: tongue	Strong
TS26: trigeminal ganglion	Strong
TS26: eye	Moderate
TS26: lung	Moderate
TS26: cerebral cortex ventricular zone	Weak

Specimen 4c: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: midbrain	Strong		4c

Specimen 5b: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: cortical plate	Present		5b

Specimen 7b: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum	Present	Regionally restricted	7b	Preferentially expressed in the internal granule cell layer.

Specimen 7e: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum	Present	Regionally restricted	7e	Preferentially expressed in the internal granule cell layer.

Specimen 8d: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: dorsal root ganglion	Present	Regionally restricted	8d	All differentiating neurons were labeled.

Specimen 8e: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: dorsal root ganglion	Present	Regionally restricted	8e	All differentiating neurons were labeled.

Specimen 8f: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: dorsal root ganglion	Present	Regionally restricted	8f	All differentiating neurons were labeled.

Specimen 11c: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: thymus primordium	Present		11c

Specimen 11d: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: thymus	Present		11d	Expression in the thymus increased between E15.5 and E18.5.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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