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Gene Expression Data
Assay Details
Assay
Reference: J:169064 Anderson KD, et al., Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2807-12
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:4943905
Gene symbol: Adgra2
Gene name: adhesion G protein-coupled receptor A2
Reporter: lacZ
Direct Detection
Results
Specimen S1 C: embryonic day 11.5; Adgra2tm1.1Vlcg/Adgra2+ (more )
Structure Level Pattern Image Note
TS19: cardiovascular system Present S1_C Expression is present in a vascular-like staining pattern in numerous locations throughout the embryo.
TS19: forelimb bud Present S1_C Expression is present in a vascular-like staining pattern in numerous locations throughout the embryo.
TS19: head Present S1_C Expression is present in a vascular-like staining pattern in numerous locations throughout the embryo.
TS19: heart Present S1_C Expression is present in a vascular-like staining pattern in numerous locations throughout the embryo.
TS19: hindlimb bud Present S1_C Expression is present in a vascular-like staining pattern in numerous locations throughout the embryo.
TS19: nose Present S1_C Expression is present in a vascular-like staining pattern in numerous locations throughout the embryo.
TS19: trunk Present S1_C Expression is present in a vascular-like staining pattern in numerous locations throughout the embryo.
Specimen S8 A: embryonic day 12.5; Adgra2tm1.1Vlcg/Adgra2tm1.1Vlcg (more )
Note: Double labeled: blue - Adgra2; brown - Pecam1 (assay MGI:4943929).
Structure Level Pattern Image Note
TS20: spinal cord vascular element Present S8_A Expression is present in the normal vasculature of the dorsal spinal cord, as well as in the glomeruloid tufts of the ventral spinal cord.
Specimen S8 B: embryonic day 12.5; Adgra2tm1.1Vlcg/Adgra2tm1.1Vlcg (more )
Note: Double labeled: blue - Adgra2; brown - Pecam1 (assay MGI:4943929).
Structure Level Pattern Image Note
TS20: forebrain vascular element Present S8_B Expression is present in the vasculature of the ganglionic eminence, which is abnormal in the mutant.
Specimen S8 C: embryonic day 12.5; Adgra2tm1.1Vlcg/Adgra2tm1.1Vlcg (more )
Note: Double labeled: blue - Adgra2; brown - Pecam1 (assay MGI:4943929).
Structure Level Pattern Image Note
TS20: cardiovascular system Present S8_C Expression is present in a peri-endothelial pattern around major arteries, such as the carotid.
TS20: embryo mesenchyme Present S8_C Expression is present in a peri-endothelial pattern around major arteries, such as the carotid.
Specimen S8 D: embryonic day 12.5; Adgra2tm1.1Vlcg/Adgra2tm1.1Vlcg (more )
Note: Double labeled: blue - Adgra2; brown - Pecam1 (assay MGI:4943929).
Structure Level Pattern Image Note
TS20: lung mesenchyme Present S8_D There is broad expression in the mesenchyme surrounding the developing bronchiolar epithelium.
TS20: lung vascular element Present S8_D
Specimen S8 E: embryonic day 12.5; Adgra2tm1.1Vlcg/Adgra2tm1.1Vlcg (more )
Structure Level Pattern Image Note
TS20: palatal shelf mesenchyme Present S8_E Expression appears to be present in the mesenchyme but not in the vessels.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory