Gene Expression Data
Assay Details
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Assay
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Reference:
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J:47261
Morsli H, et al., Development of the mouse inner ear and origin of its sensory organs. J Neurosci. 1998 May 1;18(9):3327-35
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:4943765
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Gene symbol:
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Bmp4
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Gene name:
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bone morphogenetic protein 4
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Probe:
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BMP4 cDNA4
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Probe preparation:
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Antisense RNA
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Results
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Specimen
2A:
embryonic day 9.0
(more  )
Specimen
2A:
(close  )
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Genetic Background:
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CD-1
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Age:
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embryonic day 9.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: otic pit |
Present |
Regionally restricted |
2A
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Expression is present in the posterior margin of the otic cup.
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Specimen
2B:
embryonic day 9.5
(more )
Specimen
2B:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: otocyst |
Present |
Regionally restricted |
2B
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There is diffuse expression in the posterior part of the otocyst.
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Specimen
2C:
embryonic day 10.25
(more )
Specimen
2C:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 10.25
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: otocyst |
Present |
Regionally restricted |
2C
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Expression is present in a posterior focus and a streak in the anterolateral part of the otocyst.
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Specimen
Not shown:
embryonic day 11.0
(more )
Specimen
Not shown:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 11.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: otocyst |
Present |
Regionally restricted |
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Expression is present in a posterior/ventral focus and a streak in the anterolateral part of the otocyst.
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Specimen
3A:
embryonic day 11.5
(more )
Specimen
3A:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: inner ear |
Present |
Regionally restricted |
3A
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In the dorsolateral part of the otocyst, expression is present as an anterior streak.
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Specimen
3B:
embryonic day 11.5
(more )
Specimen
3B:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: inner ear |
Present |
Regionally restricted |
3B
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In the dorsolateral part of the otocyst, expression is present as an anterior streak.
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| TS19: posterior semicircular canal |
Present |
Regionally restricted |
3B
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Expression is present in the posterior crista.
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Specimen
3D:
embryonic day 11.5
(more )
Specimen
3D:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: saccule |
Present |
Regionally restricted |
3D
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Expression is present in the lateral cochlea. It is located in the posterior pole of the otocyst and originates ventrolateral to the posterior crista.
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Specimen
3E:
embryonic day 11.5
(more )
Specimen
3E:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: saccule |
Present |
Regionally restricted |
3E
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Expression is present in the lateral cochlea. It is located in the posterior pole of the otocyst and expands ventrally to the distal tip of the cochlea anlage.
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Specimen
4A:
embryonic day 12.0
(more )
Specimen
4A:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4B:
embryonic day 12.0
(more )
Specimen
4B:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4D:
embryonic day 12.0
(more )
Specimen
4D:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: cochlea |
Present |
Regionally restricted |
4D
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The expression signal originates in the lateral part of the inner ear and expands into the greater curvature of the cochlea.
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Specimen
4E:
embryonic day 12.0
(more )
Specimen
4E:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: cochlea |
Present |
Regionally restricted |
4E
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The expression signal originates in the lateral part of the inner ear and expands into the greater curvature of the cochlea.
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Specimen
4F:
embryonic day 12.0
(more )
Specimen
4F:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: cochlea |
Present |
Regionally restricted |
4F
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The expression signal originates in the lateral part of the inner ear and expands into the greater curvature of the cochlea.
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Specimen
5A:
embryonic day 12.0
(more )
Note: The pictured specimen is a three-dimensional reconstruction.
Specimen
5A:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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The pictured specimen is a three-dimensional reconstruction.
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Specimen
5B:
embryonic day 12.0
(more )
Note: The pictured specimen is a three-dimensional reconstruction.`
Specimen
5B:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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The pictured specimen is a three-dimensional reconstruction.`
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Specimen
5C:
embryonic day 13.0
(more )
Note: The pictured specimen is a three-dimensional reconstruction.
Specimen
5C:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 13.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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The pictured specimen is a three-dimensional reconstruction.
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Specimen
5D:
embryonic day 13.0
(more )
Note: The pictured specimen is a three-dimensional reconstruction.
Specimen
5D:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 13.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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The pictured specimen is a three-dimensional reconstruction.
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Specimen
Not shown:
embryonic day 14.0
(more )
Specimen
Not shown:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 14.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
Not shown:
embryonic day 15.0
(more )
Specimen
Not shown:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
Not shown:
embryonic day 16.0
(more )
Specimen
Not shown:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 16.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: semicircular canal |
Present |
Regionally restricted |
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Expression is present in the supporting cells of the cristae.
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| TS24: utricle |
Present |
Regionally restricted |
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Expression is present in the supporting cells of the macula utriculi.
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| TS24: saccule |
Present |
Regionally restricted |
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Expression is present in the supporting cells of the macula sacculi.
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| TS24: cochlea |
Present |
Regionally restricted |
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Expression is present in the lateral cochlea, in the greater curvature.
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Specimen
Not shown:
embryonic day 18.0
(more )
Specimen
Not shown:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cochlea |
Present |
Regionally restricted |
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Expression is present in the lateral cochlea, in the greater curvature.
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Specimen
6A:
postnatal day 1
(more )
Specimen
6A:
(close )
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Genetic Background:
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CD-1
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: organ of Corti |
Present |
Regionally restricted |
6A
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Expression is present in the Hensen's and/or Claudius' cells located lateral to the outer hair cells.
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| TS27: cochlea |
Present |
Regionally restricted |
6A
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Expression is present in the mesenchyme surrounding the cochlea.
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