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Gene Expression Data
Assay Details
Assay
Reference: J:27413 Bulfone A, et al., T-brain-1: a homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex. Neuron. 1995 Jul;15(1):63-78
Assay type: RNA in situ
MGI Accession ID: MGI:4838635
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Probe: Tes-56
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen not shown: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Absent

Specimen not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Absent

Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Absent

Specimen 3a: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: telencephalon Present Regionally restricted 3a Expression first detected in the rostroventral region of the telencephalon, in a single layer of superficial cells in the mantle zone.

Specimen not shown: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: telencephalon Present Regionally restricted Expression in the preplate.
TS16: telencephalon ventricular layer Absent No expression in the ventricular zone.

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted Expression extends caudodorsally to cover much of the telencephalon. Clusters of expressing cells are connected in a reticular pattern. No expression in the dorsal midline.

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex intermediate zone Present
TS20: cortical plate Present

Specimen 3b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 3b Expression in distinct bands of cells in the telencephalon. The more dorsal band is wider and extends caudally from the anlage of the olfactory bulb to the caudal pole of the telencephalon.

Specimen 3c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 3c The more ventral band also connects the olfactory bulb to the caudal pole of the telencephalon

Specimen 3d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon mantle layer Present 3d

Specimen 3d': embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 3d' Expression restricted to clusters of cells in the outermost layer of the dorsolateral cortex.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory