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Gene Expression Data
Assay Details
Assay
Reference: J:161188 Pewzner-Jung Y, et al., A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy. J Biol Chem. 2010 Apr 2;285(14):10911-23
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4819184
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175; #9661)
Detection system: Secondary antibody
Assay notes: Antibody detects cleaved Caspase 3.
Results
Specimen 5C WT: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: liver Present 5C WT

Specimen 5C null: postnatal day 30; Cers2Gt(S16-4B1)Sor/Cers2Gt(S16-4B1)Sor (more )
Structure Level Pattern Image Note
TS28: liver Present 5C CerS2 -/- There is an increase in apoptotic cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory