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Gene Expression Data
Assay Details
Assay
Reference: J:91624 Aller MI, et al., Cerebellar granule cell Cre recombinase expression. Genesis. 2003 Jun;36(2):97-103
Assay type: Recombinase reporter
MGI Accession ID: MGI:4457058
Gene symbol: Tg(Gabra6-cre)CWwis
Gene name: transgene insertion C, W Wisden
Reporter: lacZ
Direct Detection
Results
Specimen Fig. 2c: postnatal; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Gabra6-cre)CWwis/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Strong Ubiquitous 2c
TS28: pontine nucleus Ambiguous Scattered 2c Very little recombination is observed in pontine nuclei.
TS28: neocortex Present Non-Uniform 2c Staining is variable with some cortical areas showing almost no staining.
Specimen Fig. 3e: postnatal adult; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Gabra6-cre)CWwis/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Ubiquitous 3e
TS28: cerebellum molecular layer Present Single cells 3e Staining is observed in some Purkinje cells.
Specimen Fig. 3f: postnatal adult; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Gabra6-cre)CWwis/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present 3f Staining is observed in nuclei of granule cells.
TS28: cerebellum molecular layer Present Single cells 3f Staining is observed in some Purkinje cells.
Specimen Fig. 3g: postnatal adult; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Gabra6-cre)CWwis/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: neocortex Present Scattered 3g Staining is observed in cells in transverse comlumns.
Specimen Fig. 3h: postnatal adult; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Gabra6-cre)CWwis/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hippocampus Present Scattered 3h
TS28: inferior colliculus Present Scattered 3h
TS28: superior colliculus Present Scattered 3h
TS28: midbrain Present Scattered 3h
Specimen not shown: postnatal adult; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Gabra6-cre)CWwis/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: deep cerebellar nucleus Present Scattered Staining is observed in occasional cells.
Specimen Fig. 4 P5: postnatal day 5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Gabra6-cre)CWwis/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Ambiguous 4_P5 Little or no staining (recombination) is observed.
TS28: deep cerebellar nucleus Present Single cells 4_P5 Ectopic staining is observed.
TS28: cerebellum external granule cell layer Absent 4_P5
Specimen Fig. 4 P7: postnatal day 7; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Gabra6-cre)CWwis/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Ambiguous 4_P7 Little or no staining (recombination) is observed.
TS28: deep cerebellar nucleus Present Scattered 4_P7 Ectopic staining is observed.
TS28: cerebellum external granule cell layer Absent 4_P7
Specimen Fig. 4 P14: postnatal day 14; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Gabra6-cre)CWwis/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Present Ubiquitous 4_P14 Staining is observed throughout the layer with some Purkinje cells showing recombination.
TS28: deep cerebellar nucleus Present Single cells 4_P14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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