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Gene Expression Data
Assay Details
Assay
Reference: J:17814 Reponen P, et al., High expression of 92-kD type IV collagenase (gelatinase B) in the osteoclast lineage during mouse development. J Cell Biol. 1994 Mar;124(6):1091-1102
Assay type: RNA in situ
MGI Accession ID: MGI:4443349
Gene symbol: Mmp9
Gene name: matrix metallopeptidase 9
Probe: pSP65 92b
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2A,B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forearm mesenchyme Present Regionally restricted 2A/B Intense expression in mesenchymal cells around developing cartilages of the radius and ulna.

Specimen 2C,D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hand mesenchyme Strong Single cells 2C/D Intense expression in single cells in the perichondrium of the metacarpal cartilages.
TS23: forelimb digit mesenchyme Present Single cells 2C/D Expression in single cells localized in the perichondrium at the tips of the digits.

Specimen 2E,F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forelimb skeleton Strong Regionally restricted 2E/F Very intense expression in the ossifying regions of the long bones, in large agggregates of single cells in the growth plates at sites of endochondral ossification.
TS24: forelimb mesenchyme Present Regionally restricted 2E/F Expression at many sites in the perichondrium and periosteum.

Specimen 3A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mandible mesenchyme Strong Regionally restricted 3A

Specimen 3B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mandible Strong Spotted 3B Spots of strong expression in central area of the upper and lower jaw (maxillary and mandibular processes).
TS22: maxilla Strong Spotted 3B Spots of strong expression in central area of the upper and lower jaw (maxillary and mandibular processes).

Specimen 3D,E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: jaw Strong Single cells 3D/E Strong expression in single cells in the developing jaw bones.

Specimen 4A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: mandible Strong Widespread 4A Intense expression throughout the developing bone of the mandible.
TS26: lower jaw tooth Absent 4A

Specimen 4B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: mandible Strong Regionally restricted 4B Expression in large numbers of cells at the site of endochondral ossification beneath the condylar cartilage.

Specimen 4C: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: mandible Very strong Regionally restricted 4C Expecially intense expression in the area of the bone through which the incisor is about to erupt.

Specimen 4D,E: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: mandible Strong Regionally restricted 4D/E Expression in the bone is most intense at the resorptive surface around the growing tooth germ.

Specimen 5B,E: postnatal week 2 (more )
Structure Level Pattern Image Note
TS28: forelimb Strong Single cells 5B , 5E Intense expression in cells with a similar distribution as osteoclasts.

Specimen 6A,B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hair follicle Absent 6A/B
TS22: skin Absent 6A/B

Specimen 6C,D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: clavicle cartilage condensation Present Spotted 6C/D Spots of expression in the periosteum of the clavicle.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Absent
TS22: salivary gland Absent

Specimen 6E,F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: metanephros Absent 6E/F

Specimen 6G,H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: mammary gland Absent 6G/H

Specimen 7A,B: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: lung Absent 7A/B

Specimen 7C,D: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: heart Absent 7C/D

Specimen 7E,F: postnatal adult (more )
Note: Bone marrow from adult femur.
Structure Level Pattern Image Note
TS28: bone marrow Present Single cells 7E/F

Specimen 7G,H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: intestine Absent 7G/H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory