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Gene Expression Data
Assay Details
Assay
Reference: J:154319 Alazami AM, et al., FREM1 mutations cause bifid nose, renal agenesis, and anorectal malformations syndrome. Am J Hum Genet. 2009 Sep;85(3):414-8
Assay type: RNA in situ
MGI Accession ID: MGI:4431352
Gene symbol: Frem1
Gene name: Fras1 related extracellular matrix protein 1
Probe: Frem1 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: The authors did not specify which probe was used in this assay (either Frem1 cDNA1: MGI:4431347, or Frem1 cDNA2: MGI:4431349), both probes gave identical results.
Results
Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head Strong Regionally restricted 2A Expression is in the snout region.
TS19: nose Strong 2A
Specimen 2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: nose Strong Regionally restricted 2B Expression is in the midline where the two medial nasal processes fuse.
Specimen 2C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: nose Strong Regionally restricted 2C Expression is in the epithelial-mesenchymal transitional region at the midline.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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