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Gene Expression Data
Assay Details
Assay
Reference: J:146657 Witte F, et al., Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. Gene Expr Patterns. 2009 Apr;9(4):215-23
Assay type: RNA in situ
MGI Accession ID: MGI:4397449
Gene symbol: Dkk2
Gene name: dickkopf WNT signaling pathway inhibitor 2
Probe: Dkk2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2H WM: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 2H Expression is surrounding cartilaginous anlagen.
TS20: forelimb interdigital region mesenchyme Present 2H

Specimen 2h sxn: embryonic day 12.5 (more )
Note: Vibratome section
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 2h Expression is surrounding cartilaginous anlagen.

Specimen 2I WM: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted 2I Expression is below the epidermis and in mesenchyme around the cartilage.

Specimen 2i sxn: embryonic day 13.5 (more )
Note: Vibratome section
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted 2i Expression is below the epidermis and in mesenchyme around the cartilage.

Specimen 2J,j: embryonic day 13.5 (more )
Note: (j) is a higher magnification of the boxed area in (J).
Structure Level Pattern Image Note
TS21: hand mesenchyme Strong Regionally restricted 2J , 2j Expression is in cells flanking the future joint.
TS21: forelimb interdigital region mesenchyme Present 2j , 2J

Specimen S8 E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud Absent S8_Dkk2 E9.5

Specimen S8 E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Absent S8_Dkk2 E10.5

Specimen S8 E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted S8_Dkk2 E11.5 Expression is in the proximal mesenchyme.

Specimen S8 E12.5 WM: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb interdigital region mesenchyme Present S8_Dkk2 E12.5
TS20: hand mesenchyme Present S8_Dkk2 E12.5

Specimen S8 E12.5 sxn: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted S8_Dkk2 E12.5 vibratome Expression is surrounding cartilaginous anlagen.
TS20: forelimb interdigital region mesenchyme Present S8_Dkk2 E12.5 vibratome

Specimen S8 E13.5 WM: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted S8_Dkk2 E13.5 Expression is below the epidermis and in mesenchyme around the cartilage.

Specimen S8 E13.5 sxn: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present S8_Dkk2 E13.5 vibratome Expression is below the epidermis and in mesenchyme around the cartilage.

Specimen S8 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present S8_Dkk2 E13.5 paraffin Expression is below the epidermis and in mesenchyme around the cartilage.

Specimen S8 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb mesenchyme Absent S8_Dkk2 E15.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory