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Gene Expression Data
Assay Details
Assay
Reference: J:112339 La Torre A, et al., Expression pattern of ACK1 tyrosine kinase during brain development in the mouse. Gene Expr Patterns. 2006 Oct 2;6(8):886-892
Assay type: RNA in situ
MGI Accession ID: MGI:4361550
Gene symbol: Tnk2
Gene name: tyrosine kinase, non-receptor, 2
Probe: Ack1/Py1k cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hippocampus Strong 1A
TS22: neocortex Strong 1A
TS22: thalamus Strong 1A
TS22: ganglionic eminence Strong Regionally restricted 1A Expression is in the rostral migratory pathway.

Specimen 1B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Strong 1B
TS26: dentate gyrus Strong 1B
TS26: hippocampus Strong 1B
TS26: thalamus Strong 1B

Specimen 1C: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong 1C
TS28: thalamus Strong 1C
TS28: hippocampus Strong 1C Expression is particularly strong in interneurons located parallel to the hippocampal fissure and in Mossy cells of hilus.
TS28: dentate gyrus Strong 1C
TS28: hippocampus CA1 Strong 1C
TS28: hippocampus CA3 Strong 1C

Specimen 1D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: main olfactory bulb Present Regionally restricted 1D Expression is in the mitral cells and glomerular cells.

Specimen 1E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb Present Regionally restricted 1E Expression is in the mitral cells and glomerular cells.

Specimen 1F: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 1F
TS28: main olfactory bulb mitral cell layer Present 1F

Specimen 1G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Strong 1G
TS28: main olfactory bulb mitral cell layer Strong 1G

Specimen 1H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cortical plate Very strong 1H

Specimen 1I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Very strong 1I

Specimen 1J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cortical plate Very strong 1J

Specimen 1K: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cortical layer II Very strong 1K
TS27: cortical layer III Very strong 1K
TS27: cortical layer IV Very strong 1K
TS27: cortical layer V Very strong 1K
TS27: cortical layer VI Very strong 1K

Specimen 1L: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer II Very strong 1L
TS28: cortical layer III Very strong 1L
TS28: cortical layer IV Very strong 1L
TS28: cortical layer VI Very strong 1L
TS28: cortical layer V Very strong 1L Expression was stronger in layer V.

Specimen 1M: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hippocampus Present 1M

Specimen 1N: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 1N Expression is also in precursor cells of the dentate gyrus.

Specimen 1O: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: hippocampus Strong 1O Expression is particularly strong in interneurons located parallel to the hippocampal fissure and in Mossy cells of hilus.
TS27: dentate gyrus Strong 1O
TS27: hippocampus CA1 Strong 1O
TS27: hippocampus CA3 Strong 1O

Specimen 1P: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 1P Expression is particularly strong in interneurons located parallel to the hippocampal fissure and in Mossy cells of hilus.
TS28: dentate gyrus Strong 1P
TS28: hippocampus CA1 Strong 1P
TS28: hippocampus CA3 Strong 1P

Specimen 1Q: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 1Q Expression is particularly strong in interneurons located parallel to the hippocampal fissure and in Mossy cells of hilus.
TS28: hippocampus CA3 Strong 1Q
TS28: dentate gyrus Present 1Q
TS28: hippocampus CA1 Present 1Q

Specimen 1R: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 1R Expression is particularly strong in interneurons located parallel to the hippocampal fissure and in Mossy cells of hilus.
TS28: dentate gyrus Strong 1R
TS28: hippocampus CA1 Strong 1R
TS28: hippocampus CA3 Strong 1R

Specimen 1S: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 1S Expression is particularly strong in interneurons located parallel to the hippocampal fissure and in Mossy cells of hilus.
TS28: hippocampus CA1 Present 1S
TS28: dentate gyrus granule cell layer Present Regionally restricted 1S Expression is in the subgranular zone.
TS28: hippocampus CA3 Strong 1S

Specimen 2A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: thalamus Present 2A

Specimen 2B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: thalamus Present 2B

Specimen 2C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: prethalamus Strong 2C
TS27: hypothalamus Strong Regionally restricted 2C Expression is dorsal.
TS27: hypothalamus lateral zone Strong 2C
TS27: habenula Weak 2C

Specimen 2D: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: prethalamus Present 2D
TS28: lateral geniculate nucleus Present 2D
TS28: hypothalamus Present Regionally restricted 2D Expression is dorsal.
TS28: hypothalamus lateral zone Strong 2D
TS28: habenula Weak 2D

Specimen 2E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ganglionic eminence Strong Regionally restricted 2E Expression is in the rostral migratory pathway.

Specimen 2F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: diencephalon ventricular layer Present 2F

Specimen 2G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: brain subventricular zone Present Regionally restricted 2G
TS27: diencephalon Present Regionally restricted 2G

Specimen 2H: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: diencephalon Present Regionally restricted 2H

Specimen 2I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: diencephalon Present Regionally restricted 2I

Specimen 2J: postnatal adult (more )
Structure Level Pattern Image Note
TS28: rostral migratory stream Present 2J

Specimen 2K: postnatal adult (more )
Structure Level Pattern Image Note
TS28: rostral migratory stream Present 2K

Specimen 3A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brainstem Strong 3A Expression is intense in the rhombic lip.
TS22: cerebellum Strong 3A Expression is intense in the rhombic lip.

Specimen 3B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brainstem Present Regionally restricted 3B Expression is in the external granule layer and in the Purkinje layer.
TS26: cerebellum Present Regionally restricted 3B Expression is in the external granule layer and in the Purkinje layer.
TS26: periaqueductal grey Present 3B

Specimen 3C: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cerebellum Strong 3C
TS28: cerebellum Purkinje cell layer Strong 3C

Specimen 3D: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 3D
TS28: cerebellum internal granule cell layer Strong 3D

Specimen 3E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 3E
TS28: cerebellum internal granule cell layer Strong 3E

Specimen 3F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brainstem Present Regionally restricted 3F Expression is in the floor plate and vestibulocochlear nuclei.

Specimen 3G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: pons Present Regionally restricted 3G Expression is in the pontine migratory stream and the spinotrigeminal nuclei.

Specimen 3H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: pons Present Regionally restricted 3H Expression is in solitary, vestibular, and dorsal motor nuclei.

Specimen 3I: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: facial nucleus Present 3I
TS28: gigantocellular reticular nucleus Present 3I

Specimen 3J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: medulla oblongata Present 3J

Specimen 3K: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: medulla oblongata Strong 3K

Specimen 3L: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cuneate nucleus Strong 3L
TS28: hypoglossal nucleus Strong 3L
TS28: medulla oblongata Strong 3L
TS28: solitary tract nucleus Strong 3L
TS28: trigeminal V spinal sensory nucleus Strong 3L

Specimen 3M: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cuneate nucleus Strong 3M
TS28: hypoglossal nucleus Strong 3M
TS28: medulla oblongata Strong 3M
TS28: solitary tract nucleus Strong 3M
TS28: trigeminal V spinal sensory nucleus Strong 3M

Specimen Table 1 E10: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon ventricular layer Weak
TS17: hindbrain Weak Regionally restricted Expression is in the rhombic lip.
TS17: brain Weak Regionally restricted Expression is in the floor plate of the brain stem.

Specimen Table 1 E12: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Weak Regionally restricted Expression is in the olfactory ventricle and the cingulate and retrospinal cortex.
TS20: cerebral cortex Weak Regionally restricted Expression is in the preplate.
TS20: cerebral cortex ventricular layer Weak
TS20: forebrain Weak Regionally restricted Expression is in the hippocampus primordium and is very low in the fimbria/fornix. Expression is weak in medial septum, and very weak in the amygdaloid complex.
TS20: diencephalon Strong Regionally restricted Expression is in the subcomissural organ.
TS20: thalamus Weak Non-Uniform Expression is weak in the medial thalamus and is very weak in the dorsal, ventral, and lateral thalamus.
TS20: hypothalamus Weak Regionally restricted Expression is in dorsal and arcuate nuclei.
TS20: cerebellum primordium Weak Regionally restricted Expression is in the upper and lower rhombic lip and vey weak in deep nuclei.
TS20: brainstem Weak Regionally restricted Expression is in the floor plate, facial nucleus, spinal trigeminal nucleus, reticular formation, and solitary nucleus.
TS20: ganglionic eminence Moderate

Specimen Table 1 E14: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: main olfactory bulb Strong Non-Uniform Expression is in the olfactory ventricle and mitral cell layer and is weak in the glomerular cell layer.
TS22: telencephalon Weak Regionally restricted Expression is in the piriform cortex and the cingulate and retrospinal cortex.
TS22: hippocampus Weak Non-Uniform Expression is very weak in the fimbria/fornix.
TS22: cerebral cortex ventricular layer Weak
TS22: cortical plate Weak
TS22: ganglionic eminence Strong
TS22: diencephalon Very strong Regionally restricted Expression is in the subcomissural organ.
TS22: basal forebrain Moderate Regionally restricted Expression is moderate in the medial septum and amygdaloid complex, weak in caudate-putamen, globus pallidus, and the accumbens nucleus.
TS22: basal ganglia Moderate Regionally restricted Expression is moderate in the medial septum and amygdaloid complex, weak in caudate-putamen, globus pallidus, and the accumbens nucleus.
TS22: hypothalamus Strong Regionally restricted Expression is in the arcuate nuclei, moderate in the dorsal and paraventricular nuclei, and is very weak in the ventral nuclei.
TS22: cerebellum Strong Regionally restricted Expression is in the upper rhombic lip, weak in the external germinative layer, and is very weak in the deep nuclei.
TS22: hindbrain Strong Regionally restricted Expression is in the upper rhombic lip, weak in the external germinative layer, and is very weak in the deep nuclei.
TS22: brainstem Strong Regionally restricted Expression is very strong the floor plate, strong in lower rhombic lip, pontine migratory stream, moderate in cochlear nuclei, weak in facial nucleus, spinal trigeminal nucleus, reticular formation, dorsal motor vagus, and in a few other nuclei.
TS22: cerebral cortex intermediate zone Trace
TS22: cortical subplate Trace
TS22: cerebral aqueduct Trace Regionally restricted Expression is in the periaqueductal gray area.
TS22: midbrain Weak Non-Uniform Expression is in the dorsal raphe, superior and inferior colliculus, and is very weak in the substantia nigra.
TS22: thalamus Weak Non-Uniform Expression is weak in the medial thalamus and is very weak in the dorsal, ventral, lateral thalamus, and reticular nuclei, and is absent in the lateral geniculate nuclei.
TS22: cerebral cortex marginal layer Absent
TS22: epithalamus Absent

Specimen Table 1 E16: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: main olfactory bulb Very strong Non-Uniform Expression is in the mitral layer, is strong in the olfactory ventricle and is weak in the glomerular layer.
TS24: diencephalon Very strong Regionally restricted Expression is in the subcomissural organ.
TS24: cortical plate Strong
TS24: piriform cortex Strong
TS24: superior colliculus Strong
TS24: hippocampus Strong Non-Uniform Expression is moderate in the dentate gyrus and is very weak in the fimbria/fornix.
TS24: thalamus Strong Non-Uniform Expression is in the lateral geniculate and reticulate nuclei, moderate in lateral and ventral thalamus, weak in medial and dorsal thalamus.
TS24: hypothalamus Strong Regionally restricted Expression is in paraventricular nuclei and arcuate nuclei, moderate in dorsal nuclei, and weak in ventral nuclei.
TS24: cerebral aqueduct Very strong Regionally restricted Expression is in the periaqueductal gray area.
TS24: cerebellum Strong Regionally restricted Expression is in the upper rhombic lip and Purkinje layer, moderate in the deep nuclei and the external granular layer.
TS24: brainstem Strong Regionally restricted Expression is in the floor plate and in numerous nuclei. Absent in inferior olive.
TS24: telencephalon Moderate Regionally restricted Expression is in the cingulate and retrospinal cortex, and entorhinal cortex.
TS24: rostral migratory stream Moderate Regionally restricted Expression in subventricular zone/rostral migratory stream.
TS24: telencephalon subventricular zone Moderate Regionally restricted Expression in subventricular zone/rostral migratory stream.
TS24: caudate-putamen Moderate
TS24: cortical subplate Moderate
TS24: epithalamus Moderate
TS24: basal ganglia Moderate Regionally restricted Expression is moderate in the globus pallidus, amygdaloid complex, andaccumbens nucleus, and dorso-lateral septum, weak in medial septum and taenia tecta.
TS24: forebrain Moderate Regionally restricted Expression is moderate in the globus pallidus, amygdaloid complex, andaccumbens nucleus, and dorso-lateral septum, weak in medial septum and taenia tecta.
TS24: midbrain Moderate Regionally restricted Expression is in dorsal raphe and is weak in substantia nigra.
TS24: cerebral cortex ventricular layer Weak
TS24: inferior colliculus Weak
TS24: cerebral cortex intermediate zone Trace
TS24: ganglionic eminence Trace
TS24: cerebral cortex marginal layer Absent

Specimen Table 1 E18: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb Very strong Regionally restricted Expression is in the mitral cell layer, strong in the granular layer, and is weak in the glomerular layer.
TS26: caudate-putamen Strong
TS26: cortical plate Strong
TS26: dentate gyrus Strong
TS26: hippocampus CA1 Strong
TS26: hippocampus CA2 Strong
TS26: periaqueductal grey Strong
TS26: piriform cortex Strong
TS26: superior colliculus Strong
TS26: telencephalon Strong Regionally restricted Expression is in the cingulate and retrospinal cortex, and entorhinal cortex.
TS26: rostral migratory stream Strong Regionally restricted Expression in subventricular zone/rostral migratory stream.
TS26: telencephalon subventricular zone Strong Regionally restricted Expression in subventricular zone/rostral migratory stream.
TS26: midbrain Strong Regionally restricted Expression is in dorsal raphe and is weak in substantia nigra.
TS26: hippocampus Strong Regionally restricted Expression is in the subiculum, very weak in the fimbria/fornix, and absent in alveus.
TS26: forebrain Strong Regionally restricted Expression is in the dorso-lateral septum, taenia tecta, and amygdaloid complex, moderate in globus pallidus, and accumbens nucleus, weak in medial septum.
TS26: diencephalon Strong Regionally restricted Expression is in the subcomissural organ.
TS26: thalamus Strong Non-Uniform Expression is in the lateral geniculate, reticulate nuclei, and ventral thalamus, moderate in lateral, medial and dorsal thalamus.
TS26: hypothalamus Strong Regionally restricted Expression is in paraventricular nuclei and arcuate nuclei, moderate in dorsal nuclei, and weak in ventral nuclei.
TS26: cortical subplate Moderate
TS26: epithalamus Moderate
TS26: hippocampus CA3 Moderate
TS26: cerebellum Strong Regionally restricted Expression is strong in the Purkinje layer and moderate in the upper rhombic lip, the deep nuclei and the external granular layer.
TS26: brainstem Strong Regionally restricted Expression is in the floor plate and in numerous nuclei.
TS26: brainstem nucleus Strong Regionally restricted Expression is in the floor plate and in numerous nuclei.
TS26: cerebral cortex ventricular zone Weak
TS26: inferior colliculus Weak
TS26: cerebral cortex intermediate zone Trace
TS26: cerebral cortex marginal zone Absent

Specimen Table 1 P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebellum internal granule cell layer Very strong
TS27: hippocampus CA1 Very strong
TS27: hippocampus CA2 Very strong
TS27: lateral geniculate nucleus Very strong
TS27: main olfactory bulb mitral cell layer Very strong
TS27: neocortex layer Strong Regionally restricted Expression is in the cortical plate, moderate in the subplate, weak in the ventricular zone.
TS27: thalamus Strong Regionally restricted Strong to moderate expression in ventral, medial, and lateral thalamus.
TS27: amygdala Strong
TS27: arcuate nucleus Strong
TS27: cingulate cortex Strong
TS27: cochlear nucleus Strong
TS27: dentate gyrus Strong
TS27: dorsal motor nucleus of vagus nerve Strong
TS27: entorhinal cortex Strong
TS27: periaqueductal grey Strong
TS27: piriform cortex Strong
TS27: reticular thalamic nucleus Strong
TS27: solitary tract nucleus Strong
TS27: subiculum Strong
TS27: superior colliculus Strong
TS27: taenia tecta Strong
TS27: trigeminal V spinal sensory nucleus Strong
TS27: brainstem Strong Regionally restricted Expression is in floor plate and tegmental pontine nuclei.
TS27: accumbens nucleus Moderate
TS27: caudate-putamen Moderate
TS27: cerebellum external granule cell layer Moderate
TS27: cuneate nucleus Moderate
TS27: deep cerebellar nucleus Moderate
TS27: dorsal raphe nucleus Moderate
TS27: dorsal thalamus Moderate
TS27: epithalamus Moderate
TS27: facial nucleus Moderate
TS27: globus pallidus Moderate
TS27: habenula Moderate
TS27: hippocampus CA3 Moderate
TS27: main olfactory bulb glomerular layer Moderate
TS27: main olfactory bulb granule cell layer Moderate
TS27: vestibular nucleus Moderate
TS27: cerebral aqueduct Moderate Regionally restricted Expression is in the subcomissural organ.
TS27: rostral migratory stream Present Regionally restricted Expression is in the subventricular zone/rostral migratory stream.
TS27: telencephalon subventricular zone Present Regionally restricted Expression is in the subventricular zone/rostral migratory stream.
TS27: telencephalon septum Strong Regionally restricted Expression strong in dorso-lateral septum, weak in medial septum.
TS27: hypothalamic nucleus Moderate Regionally restricted Moderate in dorsal nuclei, weak in ventral nuclei.
TS27: brainstem reticular formation Weak
TS27: hypoglossal nucleus Weak
TS27: inferior colliculus Weak
TS27: inferior olivary nucleus Weak
TS27: paraventricular hypothalamic nucleus Weak
TS27: substantia nigra Weak
TS27: pons Weak Regionally restricted Expression is in the pontine migratory stream.
TS27: fimbria hippocampus Trace
TS27: hippocampus Trace Regionally restricted Expression is in the alveus.

Specimen Table 1 P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Very strong
TS28: dentate gyrus Very strong
TS28: hippocampus CA1 Very strong
TS28: hippocampus CA2 Very strong
TS28: lateral geniculate nucleus Very strong
TS28: main olfactory bulb mitral cell layer Very strong
TS28: amygdala Strong
TS28: arcuate nucleus Strong
TS28: cingulate cortex Strong
TS28: cochlear nucleus Strong
TS28: cortical layer IV Strong
TS28: cortical layer V Strong
TS28: cortical layer VI Strong
TS28: deep cerebellar nucleus Strong
TS28: dorsal motor nucleus of vagus nerve Strong
TS28: dorsal raphe nucleus Strong
TS28: entorhinal cortex Strong
TS28: hippocampus CA3 Strong
TS28: periaqueductal grey Strong
TS28: piriform cortex Strong
TS28: reticular thalamic nucleus Strong
TS28: solitary tract nucleus Strong
TS28: subiculum Strong
TS28: superior colliculus Strong
TS28: taenia tecta Strong
TS28: trigeminal V spinal sensory nucleus Strong
TS28: hippocampus Strong Regionally restricted Expression is in interneurons, trace in alveus.
TS28: rostral migratory stream Moderate Regionally restricted Expression is moderate in the subventricular zone/rostral migratory stream.
TS28: telencephalon subventricular zone Moderate Regionally restricted Expression is moderate in the subventricular zone/rostral migratory stream.
TS28: telencephalon septum Strong Regionally restricted Expression strong in dorso-lateral septum, moderate in medial septum.
TS28: thalamus Strong Regionally restricted Strong to moderate expression in ventral, medial, and lateral thalamus.
TS28: hypothalamus Strong Regionally restricted Moderate in dorsal nuclei, strong in ventral nuclei.
TS28: brainstem Strong Regionally restricted Expression is in tegmental pontine nuclei.
TS28: accumbens nucleus Moderate
TS28: brainstem reticular formation Moderate
TS28: cerebellum external granule cell layer Moderate
TS28: cortical layer II Moderate
TS28: cortical layer III Moderate
TS28: cuneate nucleus Moderate
TS28: dorsal thalamus Moderate
TS28: facial nucleus Moderate
TS28: globus pallidus Moderate
TS28: hypoglossal nucleus Moderate
TS28: main olfactory bulb glomerular layer Moderate
TS28: main olfactory bulb granule cell layer Moderate
TS28: vestibular nucleus Moderate
TS28: cerebral aqueduct Moderate Regionally restricted Expression is in the subcomissural organ.
TS28: area postrema Weak
TS28: caudate-putamen Weak
TS28: cerebellum internal granule cell layer Weak
TS28: epithalamus Weak
TS28: inferior colliculus Weak
TS28: inferior olivary nucleus Weak
TS28: substantia nigra Weak
TS28: cerebellum molecular layer Trace
TS28: fimbria hippocampus Trace
TS28: paraventricular hypothalamic nucleus Trace

Specimen Table 1 P10: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Very strong
TS28: cingulate cortex Very strong
TS28: cortical layer IV Very strong
TS28: cortical layer V Very strong
TS28: cortical layer VI Very strong
TS28: dentate gyrus Very strong
TS28: hippocampus CA1 Very strong
TS28: hippocampus CA2 Very strong
TS28: lateral geniculate nucleus Very strong
TS28: main olfactory bulb mitral cell layer Very strong
TS28: piriform cortex Very strong
TS28: subiculum Very strong
TS28: hippocampus Very strong Regionally restricted Expression is in interneurons, trace in the alveus.
TS28: rostral migratory stream Weak Regionally restricted Expression is weak in the subventricular zone/rostral migratory stream.
TS28: telencephalon subventricular zone Weak Regionally restricted Expression is weak in the subventricular zone/rostral migratory stream.
TS28: telencephalon septum Very strong Regionally restricted Expression ver strong in dorso-lateral septum; moderate in medial septum.
TS28: amygdala Strong
TS28: brainstem reticular formation Strong
TS28: cortical layer II Strong
TS28: cortical layer III Strong
TS28: cuneate nucleus Strong
TS28: deep cerebellar nucleus Strong
TS28: dorsal motor nucleus of vagus nerve Strong
TS28: dorsal raphe nucleus Strong
TS28: entorhinal cortex Strong
TS28: facial nucleus Strong
TS28: hippocampus CA3 Strong
TS28: hypoglossal nucleus Strong
TS28: inferior colliculus Strong
TS28: periaqueductal grey Strong
TS28: solitary tract nucleus Strong
TS28: superior colliculus Strong
TS28: taenia tecta Strong
TS28: trigeminal V spinal sensory nucleus Strong
TS28: vestibular nucleus Strong
TS28: thalamus Strong Non-Uniform Strong to moderate expression in ventral, medial, and lateral thalamus.
TS28: hypothalamus Strong Regionally restricted Expression is in dorsal nuclei and ventral nuclei.
TS28: brainstem Strong Regionally restricted Expression is in tegmental pontine nuclei.
TS28: accumbens nucleus Moderate
TS28: arcuate nucleus Moderate
TS28: area postrema Moderate
TS28: cerebellum external granule cell layer Moderate
TS28: cerebellum internal granule cell layer Moderate
TS28: cerebellum molecular layer Moderate
TS28: cochlear nucleus Moderate
TS28: dorsal thalamus Moderate
TS28: globus pallidus Moderate
TS28: main olfactory bulb glomerular layer Moderate
TS28: main olfactory bulb granule cell layer Moderate
TS28: reticular thalamic nucleus Moderate
TS28: cerebral aqueduct Moderate Regionally restricted Expression is in the subcomissural organ.
TS28: caudate-putamen Weak
TS28: epithalamus Weak
TS28: inferior olivary nucleus Weak
TS28: substantia nigra Weak
TS28: fimbria hippocampus Trace
TS28: paraventricular hypothalamic nucleus Trace

Specimen Table 1 P15: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Very strong
TS28: cingulate cortex Very strong
TS28: cortical layer IV Very strong
TS28: cortical layer V Very strong
TS28: cortical layer VI Very strong
TS28: deep cerebellar nucleus Very strong
TS28: dentate gyrus Very strong
TS28: hippocampus CA1 Very strong
TS28: hippocampus CA2 Very strong
TS28: lateral geniculate nucleus Very strong
TS28: main olfactory bulb mitral cell layer Very strong
TS28: piriform cortex Very strong
TS28: subiculum Very strong
TS28: vestibular nucleus Very strong
TS28: hippocampus Very strong Regionally restricted Expression is in interneurons, trace in the alveus.
TS28: rostral migratory stream Moderate Regionally restricted Expression is moderate in the subventricular zone/rostral migratory stream.
TS28: telencephalon subventricular zone Moderate Regionally restricted Expression is moderate in the subventricular zone/rostral migratory stream.
TS28: telencephalon septum Very strong Regionally restricted Expression very strong in dorso-lateral septum, moderate in medial septum.
TS28: brainstem reticular formation Strong
TS28: cortical layer II Strong
TS28: cortical layer III Strong
TS28: cuneate nucleus Strong
TS28: dorsal motor nucleus of vagus nerve Strong
TS28: dorsal raphe nucleus Strong
TS28: entorhinal cortex Strong
TS28: facial nucleus Strong
TS28: hippocampus CA3 Strong
TS28: hypoglossal nucleus Strong
TS28: inferior colliculus Strong
TS28: periaqueductal grey Strong
TS28: solitary tract nucleus Strong
TS28: superior colliculus Strong
TS28: taenia tecta Strong
TS28: thalamus Strong Non-Uniform Strong to moderate expression in ventral, medial, and lateral thalamus.
TS28: hypothalamus Strong Regionally restricted Expression is in dorsal nuclei and ventral nuclei.
TS28: brainstem Strong Regionally restricted Expression is in tegmental pontine nuclei.
TS28: accumbens nucleus Moderate
TS28: amygdala Moderate
TS28: arcuate nucleus Moderate
TS28: area postrema Moderate
TS28: cerebellum internal granule cell layer Moderate
TS28: cerebellum molecular layer Moderate
TS28: cochlear nucleus Moderate
TS28: dorsal thalamus Moderate
TS28: globus pallidus Moderate
TS28: main olfactory bulb glomerular layer Moderate
TS28: main olfactory bulb granule cell layer Moderate
TS28: reticular thalamic nucleus Moderate
TS28: substantia nigra Moderate
TS28: trigeminal V spinal sensory nucleus Moderate
TS28: cerebral aqueduct Moderate Regionally restricted Expression is in the subcomissural organ.
TS28: caudate-putamen Weak
TS28: epithalamus Weak
TS28: inferior olivary nucleus Weak
TS28: fimbria hippocampus Trace
TS28: paraventricular hypothalamic nucleus Trace

Specimen Table 1 P21: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cingulate cortex Very strong
TS28: cortical layer IV Very strong
TS28: cortical layer V Very strong
TS28: cortical layer VI Very strong
TS28: deep cerebellar nucleus Very strong
TS28: facial nucleus Very strong
TS28: hippocampus CA3 Very strong
TS28: main olfactory bulb mitral cell layer Very strong
TS28: piriform cortex Very strong
TS28: subiculum Very strong
TS28: vestibular nucleus Very strong
TS28: hippocampus Very strong Regionally restricted Expression is in interneurons, trace in the alveus.
TS28: cerebellum Purkinje cell layer Strong
TS28: cortical layer II Strong
TS28: cortical layer III Strong
TS28: cuneate nucleus Strong
TS28: dentate gyrus Strong
TS28: dorsal motor nucleus of vagus nerve Strong
TS28: dorsal raphe nucleus Strong
TS28: entorhinal cortex Strong
TS28: hippocampus CA1 Strong
TS28: hippocampus CA2 Strong
TS28: hypoglossal nucleus Strong
TS28: inferior colliculus Strong
TS28: lateral geniculate nucleus Strong
TS28: periaqueductal grey Strong
TS28: solitary tract nucleus Strong
TS28: superior colliculus Strong
TS28: taenia tecta Strong
TS28: rostral migratory stream Moderate Regionally restricted Expression is moderate in the subventricular zone/rostral migratory stream.
TS28: telencephalon subventricular zone Moderate Regionally restricted Expression is moderate in the subventricular zone/rostral migratory stream.
TS28: telencephalon septum Very strong Regionally restricted Expression very strong in dorso-lateral septum, moderate in medial septum.
TS28: thalamus Strong Non-Uniform Strong to moderate expression in ventral, medial, and lateral thalamus.
TS28: hypothalamus Strong Regionally restricted Expression is in dorsal nuclei and moderate in ventral nuclei.
TS28: brainstem Strong Regionally restricted Expression is in tegmental pontine nuclei.
TS28: accumbens nucleus Moderate
TS28: amygdala Moderate
TS28: arcuate nucleus Moderate
TS28: area postrema Moderate
TS28: brainstem reticular formation Moderate
TS28: cerebellum internal granule cell layer Moderate
TS28: cochlear nucleus Moderate
TS28: dorsal thalamus Moderate
TS28: epithalamus Moderate
TS28: globus pallidus Moderate
TS28: main olfactory bulb glomerular layer Moderate
TS28: main olfactory bulb granule cell layer Moderate
TS28: reticular thalamic nucleus Moderate
TS28: substantia nigra Moderate
TS28: trigeminal V spinal sensory nucleus Moderate
TS28: caudate-putamen Weak
TS28: inferior olivary nucleus Weak
TS28: cerebral aqueduct Weak Regionally restricted Expression is in the subcomissural organ.
TS28: cerebellum molecular layer Trace
TS28: fimbria hippocampus Trace
TS28: paraventricular hypothalamic nucleus Trace

Specimen Table 1 A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cingulate cortex Very strong
TS28: cortical layer IV Very strong
TS28: cortical layer V Very strong
TS28: cortical layer VI Very strong
TS28: deep cerebellar nucleus Very strong
TS28: facial nucleus Very strong
TS28: hippocampus CA3 Very strong
TS28: main olfactory bulb mitral cell layer Very strong
TS28: piriform cortex Very strong
TS28: subiculum Very strong
TS28: vestibular nucleus Very strong
TS28: hippocampus Very strong Regionally restricted Expression is in interneurons, trace in the alveus.
TS28: cerebellum Purkinje cell layer Strong
TS28: cortical layer II Strong
TS28: cortical layer III Strong
TS28: cuneate nucleus Strong
TS28: dentate gyrus Strong
TS28: dorsal motor nucleus of vagus nerve Strong
TS28: dorsal raphe nucleus Strong
TS28: entorhinal cortex Strong
TS28: hippocampus CA1 Strong
TS28: hippocampus CA2 Strong
TS28: hypoglossal nucleus Strong
TS28: inferior colliculus Strong
TS28: lateral geniculate nucleus Strong
TS28: periaqueductal grey Strong
TS28: solitary tract nucleus Strong
TS28: superior colliculus Strong
TS28: taenia tecta Strong
TS28: rostral migratory stream Strong Regionally restricted Expression is strong in the subventricular zone/rostral migratory stream.
TS28: telencephalon subventricular zone Strong Regionally restricted Expression is strong in the subventricular zone/rostral migratory stream.
TS28: telencephalon septum Very strong Regionally restricted Expression very strong in dorso-lateral septum; moderate in medial septum,
TS28: thalamus Strong Regionally restricted Strong to moderate expression in ventral, medial, and lateral thalamus.
TS28: hypothalamus Strong Regionally restricted Expression is in dorsal nuclei and moderate in ventral nuclei.
TS28: brainstem Strong Regionally restricted Expression is in tegmental pontine nuclei.
TS28: accumbens nucleus Moderate
TS28: amygdala Moderate
TS28: arcuate nucleus Moderate
TS28: area postrema Moderate
TS28: brainstem reticular formation Moderate
TS28: cerebellum internal granule cell layer Moderate
TS28: cochlear nucleus Moderate
TS28: dorsal thalamus Moderate
TS28: epithalamus Moderate
TS28: globus pallidus Moderate
TS28: main olfactory bulb glomerular layer Moderate
TS28: main olfactory bulb granule cell layer Moderate
TS28: reticular thalamic nucleus Moderate
TS28: substantia nigra Moderate
TS28: trigeminal V spinal sensory nucleus Moderate
TS28: caudate-putamen Weak
TS28: inferior olivary nucleus Weak
TS28: cerebral aqueduct Weak Regionally restricted Expression is in the subcomissural organ.
TS28: cerebellum molecular layer Trace
TS28: fimbria hippocampus Trace
TS28: paraventricular hypothalamic nucleus Trace


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory