Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:152591
Moffatt P, et al., Bril: a novel bone-specific modulator of mineralization. J Bone Miner Res. 2008 Sep;23(9):1497-508
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:4360499
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Gene symbol:
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Ifitm5
|
Gene name:
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interferon induced transmembrane protein 5
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Probe:
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Bril cDNA1
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Probe preparation:
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Antisense RNA
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Visualized with:
|
Autoradiography
|
|
Results
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Specimen
3C:
embryonic day 14.5
(more )
Specimen
3C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Specimen
3D:
embryonic day 16.5
(more )
Specimen
3D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 16.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: tibia |
Present |
Regionally restricted |
3D
,
3B
|
There is strong expression in the metaphyseal region. Expression is localized at the periphery of the bone, as well as on osteoblasts juxtaposed to mineralized trabeculae. Proliferating and resting zone growth plate chondrocytes are negative.
|
TS24: lower leg mesenchyme |
Absent |
|
3D
,
3B
|
No significant expression is detected in the surrounding muscles and connective tissues.
|
TS24: lower leg skin |
Absent |
|
3B
,
3D
|
|
|