About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:36377 Carpintero P, et al., Thymosin beta10 mRNA expression during early postimplantation mouse development. FEBS Lett. 1996 Sep 23;394(1):103-6
Assay type: RNA in situ
MGI Accession ID: MGI:4358502
Gene symbol: Tmsb10
Gene name: thymosin beta 10
Probe: Tbeta10 cDNA2
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 2A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo mesenchyme Strong Regionally restricted 2A Expression is in most mesenchymal regions.
TS15: 1st branchial arch mandibular component mesenchyme Present 2A
TS15: 1st branchial arch maxillary component mesenchyme Present 2A
TS15: head mesenchyme Present 2A
TS15: limb mesenchyme Present 2A
TS15: trunk sclerotome Present 2A
TS15: future spinal cord Weak 2A
TS15: otocyst Weak 2A

Specimen 2B,C: embryonic day 9.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS15: skeleton Strong Regionally restricted 2C , 2B Expression is in skeletal mesenchyme.
TS15: future hindbrain Weak Regionally restricted 2B , 2C Expression is in the mantle layer in the basal plate of the caudal medulla oblongata.
TS15: neural tube lateral wall Weak Regionally restricted 2C , 2B Expression is in the rostral spinal cord in the region of differentiating motoneurons.
TS15: spinal ganglion Weak Regionally restricted 2C , 2B Expression is in the rostral spinal ganglia.
TS15: endocardial cushion Moderate 2B , 2C Low to moderate expression.

Specimen 2D,E: embryonic day 10.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS17: endocardial cushion Present 2E , 2D
TS17: head mesenchyme Present 2E , 2D
TS17: cranial ganglion Moderate Scattered 2E , 2D Low to moderate expression in the vestibular ganglion.
TS17: hindbrain mantle layer Strong Regionally restricted 2D , 2E Expression is in the mantle layer of the basal plate of the medulla.
TS17: future spinal cord Strong Regionally restricted 2E , 2D Expression is in the rostral spinal cord.
TS17: spinal ganglion Strong 2D , 2E

Specimen 2F,G: embryonic day 12.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS20: spinal cord mantle layer Strong Regionally restricted 2G , 2F Expression is in the rostral spinal cord, absent in the caudal region.
TS20: spinal ganglion Moderate 2F , 2G Low to moderate expression.
TS20: brain mantle layer Present Regionally restricted 2F , 2G Expression extends in the medulla oblongata laterally, including medial regions of the alar plate and is maximal at the midline.
TS20: medulla oblongata mantle layer Present Regionally restricted 2F , 2G Expression extends in the medulla oblongata laterally, including medial regions of the alar plate and is maximal at the midline.
TS20: cranial ganglion Present 2F , 2G
TS20: hypothalamus mantle layer Present 2F , 2G
TS20: thalamus mantle layer Present 2F , 2G
TS20: telencephalon Absent 2G , 2F
TS20: cerebellum primordium Absent 2F , 2G The authors state that the mantle layer in the cerebellar lips is inappreciable and expression is absent.

Specimen 2H,I: embryonic day 12.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS20: spinal cord mantle layer Strong Regionally restricted 2H , 2I Expression is in the rostral spinal cord, absent in the caudal area.
TS20: spinal ganglion Present Regionally restricted 2I , 2H Expression is in rostral spinal ganglia.
TS20: embryo mesenchyme Strong Regionally restricted 2H , 2I At the level of the caudal spinal cord high levels of expression are found, but it is absent in chondroid masses.
TS20: nephric duct Strong Regionally restricted 2I , 2H Expression is in the mesenchyme associated with he nephric duct.
TS20: gut mesentery Strong Regionally restricted 2H , 2I Expression is in the falciform process.
TS20: body wall Strong Regionally restricted 2H , 2I Expression is in pre-muscle bands.
TS20: limb Strong Regionally restricted 2H , 2I Expression is in pre-muscle bands.
TS20: endocardial cushion Strong 2I , 2H
TS20: cardiac muscle tissue Weak 2H , 2I Expression is weak or inappreciable.
TS20: choroid plexus Absent 2I , 2H Expression is absent in epiplexus cells (Kolmer cells).

Specimen Not shown E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: brain mantle layer Present
TS19: cranial ganglion Present
TS19: embryo mesenchyme Present
TS19: spinal ganglion Present

Specimen Not shown E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: blood Absent Expression is absent in leukocytes.
TS20: eye Weak
TS20: gut epithelium Weak
TS20: nasal cavity epithelium Weak
TS20: remnant of Rathke's pouch Weak
TS20: inner ear Weak Regionally restricted Expression is in the otocyst walls.
TS20: metanephros Weak Regionally restricted Expression is in the epithelia.
TS20: blood vessel Weak Regionally restricted Expression is in the walls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory