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Gene Expression Data
Assay Details
Assay
Reference: J:91438 DiCicco-Bloom E, et al., Embryonic expression and multifunctional actions of the natriuretic peptides and receptors in the developing nervous system. Dev Biol. 2004 Jul 1;271(1):161-75
Assay type: RNA in situ
MGI Accession ID: MGI:4355923
Gene symbol: Nppc
Gene name: natriuretic peptide type C
Probe: CNP cDNA
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 2C,D: embryonic day 14.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS22: basal columns Present 2C , 2D Expression is in motor neurons.
TS22: spinal cord dura mater Present 2D , 2C Expression is in a band surrounding the spinal cord and is localized to dura and/or cartilage primordia.
TS22: vertebral cartilage condensation Present Regionally restricted 2D , 2C Expression is in a band surrounding the spinal cord and is localized to dura and/or cartilage primordia.
TS22: spinal cord ventricular layer Very strong Regionally restricted 2D , 2C Expression is in an area in the dorsal ventricular zone.
Specimen 6A,B: embryonic day 12.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS20: hindbrain Present 6A , 6B
TS20: midbrain Present 6A , 6B
TS20: spinal cord Present Regionally restricted 6B , 6A Expression is in the dorsal spinal cord.
Specimen 6C,D: embryonic day 12.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS20: spinal cord lateral wall Present Regionally restricted 6D , 6C Expression is in the dorsal and intermediate ventricular zone and possibly in more lateral regions.
TS20: spinal cord ventricular layer Present Regionally restricted 6D , 6C Expression is in the dorsal and intermediate ventricular zone and possibly in more lateral regions.
Specimen 6E,F: embryonic day 14.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS22: hindbrain dura mater Present 6E , 6F
TS22: midbrain tegmentum Present Scattered 6F , 6E
TS22: hindbrain ventricular layer Present Regionally restricted 6E , 6F Expression is dorsal.
Specimen Not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: central nervous system Present Regionally restricted Expression is in all levels of the central nervous system caudal to the mesencephalon.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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