About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:144373 Kinameri E, et al., Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One. 2008;3(12):e3859
Assay type: RNA in situ
MGI Accession ID: MGI:3852045
Gene symbol: Prdm8
Gene name: PR domain containing 8
Results
Specimen 2A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future spinal cord Strong 2A

Specimen 2D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Strong 2D

Specimen 3A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future spinal cord Strong Regionally restricted 3A Expression was strong in the ventral ventricular zone and some postmitotic neurons.
TS19: neural tube ventricular layer Strong Regionally restricted 3A Expression was strong in the ventral ventricular zone and some postmitotic neurons.

Specimen 3B: embryonic day 11.5 (more )
Note: Double labeled: blue - Prdm8; brown - Dbx1 (assay MGI:3852058).
Structure Level Pattern Image Note
TS19: neural tube ventricular layer Present Regionally restricted 3B Expression was detected in the ventricular zone of progenitor regions p0, p1, p2 and pMN.

Specimen 3C: embryonic day 11.5 (more )
Note: Double labeled: blue - Prdm8; brown - Nkx2-2 (assay MGI:3852059).
Structure Level Pattern Image Note
TS19: neural tube ventricular layer Present Regionally restricted 3C Expression was detected in the ventricular zone of progenitor regions p0, p1, p2 and pMN.

Specimen 3L: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube mantle layer Present Regionally restricted 3L Expression was detected in both proliferating cells in the ventricular zone and adjacent postmitotic neurons in the mantle zone.
TS19: neural tube ventricular layer Present Regionally restricted 3L Expression was detected in both proliferating cells in the ventricular zone and adjacent postmitotic neurons in the mantle zone.

Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Present

Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 4C Expression was detected in the postmitotic neurons of the lateral and dorsal regions of the cortex.

Specimen 4H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 4H Expression was detected in the postmitotic neurons of the lateral and dorsal regions of the cortex.

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forebrain Present Regionally restricted Expression was detected in postmitotic neurons.

Specimen 5A: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present 5A
TS28: cortical layer III Present 5A
TS28: cortical layer IV Present 5A

Specimen 5D: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present Scattered 5D
TS28: hippocampus CA2 Present 5D
TS28: hippocampus CA3 Present 5D

Specimen 5E: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: nucleus of lateral olfactory tract Present 5E

Specimen 6A & 6A': embryonic day 14.5 (more )
Note: Fig. 6A' is a magnified image from a region of 6A.
Structure Level Pattern Image Note
TS22: telencephalon Present 6A , 6A'

Specimen 6B & 6B': embryonic day 14.5; Emx1tm1(cre)Ito/Emx1+, Hes1tm1Kag/Hes1tm1Kag, Hes3tm1Kag/Hes3tm1Kag, Hes5tm1Fgu/Hes5tm1Fgu (more )
Note: Conditional mutant. Fig. 6B' is a magnified image from a region of 6B.
Structure Level Pattern Image Note
TS22: telencephalon Present 6B' , 6B There was a large increase in the number of cells with expression in the telencephalon of the mutant compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory