Gene Expression Data
Assay Details
Assay
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Reference:
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J:144373
Kinameri E, et al., Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One. 2008;3(12):e3859
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3852045
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Gene symbol:
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Prdm8
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Gene name:
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PR domain containing 8
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Results
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Specimen
2A:
embryonic day 9.5
(more )
Specimen
2A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2D:
embryonic day 10.5
(more )
Specimen
2D:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
3A:
embryonic day 11.5
(more )
Specimen
3A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS19: future spinal cord |
Strong |
Regionally restricted |
3A
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Expression was strong in the ventral ventricular zone and some postmitotic neurons.
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TS19: neural tube ventricular layer |
Strong |
Regionally restricted |
3A
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Expression was strong in the ventral ventricular zone and some postmitotic neurons.
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Specimen
3B:
embryonic day 11.5
(more )
Note: Double labeled: blue - Prdm8; brown - Dbx1 (assay MGI:3852058).
Specimen
3B:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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Double labeled: blue - Prdm8; brown - Dbx1 (assay MGI:3852058).
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Structure |
Level |
Pattern |
Image |
Note |
TS19: neural tube ventricular layer |
Present |
Regionally restricted |
3B
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Expression was detected in the ventricular zone of progenitor regions p0, p1, p2 and pMN.
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Specimen
3C:
embryonic day 11.5
(more )
Note: Double labeled: blue - Prdm8; brown - Nkx2-2 (assay MGI:3852059).
Specimen
3C:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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Double labeled: blue - Prdm8; brown - Nkx2-2 (assay MGI:3852059).
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Structure |
Level |
Pattern |
Image |
Note |
TS19: neural tube ventricular layer |
Present |
Regionally restricted |
3C
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Expression was detected in the ventricular zone of progenitor regions p0, p1, p2 and pMN.
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Specimen
3L:
embryonic day 11.5
(more )
Specimen
3L:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS19: neural tube mantle layer |
Present |
Regionally restricted |
3L
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Expression was detected in both proliferating cells in the ventricular zone and adjacent postmitotic neurons in the mantle zone.
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TS19: neural tube ventricular layer |
Present |
Regionally restricted |
3L
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Expression was detected in both proliferating cells in the ventricular zone and adjacent postmitotic neurons in the mantle zone.
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Specimen
not shown:
embryonic day 11.5
(more )
Specimen
not shown:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4C:
embryonic day 12.5
(more )
Specimen
4C:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS20: cerebral cortex |
Present |
Regionally restricted |
4C
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Expression was detected in the postmitotic neurons of the lateral and dorsal regions of the cortex.
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Specimen
4H:
embryonic day 12.5
(more )
Specimen
4H:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS20: cerebral cortex |
Present |
Regionally restricted |
4H
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Expression was detected in the postmitotic neurons of the lateral and dorsal regions of the cortex.
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Specimen
not shown:
embryonic day 16.5
(more )
Specimen
not shown:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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Not Specified
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Structure |
Level |
Pattern |
Image |
Note |
TS24: forebrain |
Present |
Regionally restricted |
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Expression was detected in postmitotic neurons.
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Specimen
5A:
postnatal day 6
(more )
Specimen
5A:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Specimen
5D:
postnatal day 6
(more )
Specimen
5D:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Specimen
5E:
postnatal day 6
(more )
Specimen
5E:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Specimen
6A & 6A':
embryonic day 14.5
(more )
Note: Fig. 6A' is a magnified image from a region of 6A.
Specimen
6A & 6A':
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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Fig. 6A' is a magnified image from a region of 6A.
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Specimen
6B & 6B':
(close )
Genetic Background:
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involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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Mutant Allele(s):
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Emx1tm1(cre)Ito/Emx1+ Hes1tm1Kag/Hes1tm1Kag Hes3tm1Kag/Hes3tm1Kag Hes5tm1Fgu/Hes5tm1Fgu
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Age:
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embryonic day 14.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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Conditional mutant. Fig. 6B' is a magnified image from a region of 6B.
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Structure |
Level |
Pattern |
Image |
Note |
TS22: telencephalon |
Present |
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6B'
,
6B
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There was a large increase in the number of cells with expression in the telencephalon of the mutant compared to wild type.
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