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Gene Expression Data
Assay Details
Assay
Reference: J:98559 Lonka L, et al., The neuronal ceroid lipofuscinosis Cln8 gene expression is developmentally regulated in mouse brain and up-regulated in the hippocampal kindling model of epilepsy. BMC Neurosci. 2005 Apr 13;6(1):27
Assay type: RT-PCR
MGI Accession ID: MGI:3848059
Gene symbol: Cln8
Gene name: CLN8 transmembrane ER and ERGIC protein
Probe: Cln8-pC, Cln8-pD
Probe preparation: labelled with SYBR green
Assay notes: Real-time quantitative RT-PCR analysis. The Cln8 specific probe (6FAM probe; MGI:3848048) included a reporter dye 6-carboxyfluorescein (FAM) and a quencher dye 6-carboxy-tetramethyl-rhodamine (TAMRA).
Results
Image: 1B ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex
heart P adult TS28: heart Present (b) Not Specified Not Specified Not Specified
brain P adult TS28: brain Present Not Specified Not Specified Not Specified
spleen P adult TS28: spleen Present (c) Not Specified Not Specified Not Specified
lung P adult TS28: lung Present (d) Not Specified Not Specified Not Specified
liver P adult TS28: liver Present (e) Not Specified Not Specified Not Specified
skeletal muscle P adult TS28: skeletal muscle Present (f) Not Specified Not Specified Not Specified
kidney P adult TS28: metanephros Present (g) Not Specified Not Specified Not Specified
testis P adult TS28: testis Present (h) Not Specified Not Specified Male
7-day E7.0 (i) TS10: embryo Present Not Specified Not Specified Not Specified
11-day E11.0 (i) TS18: embryo Present (j) Not Specified Not Specified Not Specified
15-day E15.0 (i) TS23: embryo Present Not Specified Not Specified Not Specified
17-day E17.0 (i) TS25: embryo Present Not Specified Not Specified Not Specified
Notes:
(a) The expression of Cln8 in brain, given a value of 1, was used as a control. The expression of Cln8 in the other tissues is shown as a fold of the control.
(b) Expression is 1.7-fold higher than in the brain.
(c) Expression is 2.2-fold higher than in the brain.
(d) Expression is 0.5-fold lower than in the brain.
(e) Expression is 2.5-fold higher than in the brain.
(f) Expression is 1.6-fold higher than in the brain.
(g) Expression is 0.9-fold lower than in the brain.
(h) Expression is 0.03-fold lower than in the brain.
(i) Age of embryo at noon of plug day not specified in reference.
(j) Expression is 0.6-fold lower than in the brain.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory