Gene Expression Data
Assay Details
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Assay
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Reference:
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J:136160
Joesting MS, et al., Secreted frizzled related protein 1 is a paracrine modulator of epithelial branching morphogenesis, proliferation, and secretory gene expression in the prostate. Dev Biol. 2008 May 1;317(1):161-73
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3846413
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Gene symbol:
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Mki67
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Gene name:
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antigen identified by monoclonal antibody Ki 67
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Antibody:
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Anti-Ki67 (MM1)
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
5A:
postnatal week 5
(more  )
Specimen
5A:
(close  )
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Genetic Background:
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involves: 129 * C57BL/6J
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Age:
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postnatal week 5
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: prostate epithelium |
Present |
Regionally restricted |
5A
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Expression was detected in luminal epithelial cells.
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Specimen
5B:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Sfrp1tm1Jrbn/Sfrp1tm1Jrbn
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Age:
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postnatal week 5
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: prostate epithelium |
Present |
Regionally restricted |
5B
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Mutant prostates had significantly fewer proliferating cells than wild type.
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Specimen
5D:
postnatal week 7
(more )
Specimen
5D:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Age:
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postnatal week 7
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: prostate epithelium |
Present |
Regionally restricted |
5D
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Expression was detected in luminal epithelial cells.
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Specimen
5E:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Sfrp1tm1Jrbn/Sfrp1tm1Jrbn
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Age:
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postnatal week 7
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: prostate epithelium |
Present |
Regionally restricted |
5E
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There was no significant difference in the number of proliferating cells between wild type and mutant.
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Specimen
7B:
postnatal month 5
(more )
Specimen
7B:
(close )
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Genetic Background:
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FVB/N
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Age:
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postnatal month 5
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Analysis Tools