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Gene Expression Data
Assay Details
Assay
Reference: J:142494 Nakazaki H, et al., Transcriptional regulation by Pax3 and TGFbeta2 signaling: a potential gene regulatory network in neural crest development. Int J Dev Biol. 2009;53(1):69-79
Assay type: RNA in situ
MGI Accession ID: MGI:3842386
Gene symbol: Hes1
Gene name: hes family bHLH transcription factor 1
Probe: Hes1 probe8
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen (i): embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: neural tube Present Regionally restricted 2A (i) Expression in the dorsal neural tube.
TS16: migrating neural crest Present Regionally restricted 2A (i) Expression in migrating neural crest cells.

Specimen (ii): embryonic day 10.0; Tgfb2tm1Doe/Tgfb2tm1Doe (more )
Structure Level Pattern Image Note
TS16: neural tube Present Regionally restricted 2A (ii) Slight but insignificant increase in expression levels in dorsal neural tube.
TS16: migrating neural crest Present 2A (ii) Slight but insignificant increase in expression levels.

Specimen (iii): embryonic day 10.0; Pax3Sp/Pax3Sp (more )
Structure Level Pattern Image Note
TS16: neural tube Present Regionally restricted 2A (iii) Expression was down-regulated in dorsal neural tube.
TS16: migrating neural crest Present 2A (iii) Expression was down-regulated.

Specimen (iv): embryonic day 10.0; Pax3Sp/Pax3+ (more )
Structure Level Pattern Image Note
TS16: neural tube Present Regionally restricted 2A (iv) Expression was down-regulated in dorsal neural tube.
TS16: migrating neural crest Present 2A (iv) Expression was down-regulated.

Specimen (v): embryonic day 10.0; Pax3Sp/Pax3+, Tgfb2tm1Doe/Tgfb2+ (more )
Structure Level Pattern Image Note
TS16: neural tube Present Regionally restricted 2A (v) Expression was close to wild type in the dorsal neural tube.
TS16: migrating neural crest Present 2A (v) Expression was close to wild type.

Specimen (vi): embryonic day 10.0; Pax3Sp/Pax3+, Tgfb2tm1Doe/Tgfb2tm1Doe (more )
Structure Level Pattern Image Note
TS16: neural tube Present Regionally restricted 2A (vi) Expression was close to wild type in the dorsal neural tube.
TS16: migrating neural crest Present 2A (vi) Expression was close to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory