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Gene Expression Data
Assay Details
Assay
Reference: J:147293 Chia IV, et al., Both the RGS Domain and the Six C-Terminal Amino Acids of Mouse Axin Are Required for Normal Embryogenesis. Genetics. 2009 Apr;181(4):1359-68
Assay type: Western blot
MGI Accession ID: MGI:3840878
Gene symbol: Axin1
Gene name: axin 1
Antibody: anti-Axin
Results Image: 1E
 Sample Information Bands Other Sample Information
Lane AgeStructure 130 kDa (b) 110 kDa (c) Genetic BackgroundMutant Allele(s)Sex
+/+ E10.5 (a) TS17: embryo Absent Present Not Specified Not Specified
Ax/Ax E10.5 (a) TS17: embryo Present (d) Absent involves: 129S6/SvEvTac * FVB/N Axin1tm1(Axin2)Cos/Axin1tm1(Axin2)CosNot Specified
Ax/+ E10.5 (a) TS17: embryo Present (e) Present involves: 129S6/SvEvTac * FVB/N Axin1tm2Cos/Axin1+Not Specified
deltaC6/+ E10.5 (a) TS17: embryo Weak (f) Present involves: 129S6/SvEvTac * FVB/N Axin1tm4Cos/Axin1+Not Specified
deltaC6/+ E10.5 (a) TS17: embryo Weak (f) Present involves: 129S6/SvEvTac * FVB/N Axin1tm4Cos/Axin1+Not Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Upper bands represent Myc-tagged products.
(c) Lower band is the endogenous gene product.
(d) Myc-tagged Ax allele product.
(e) The heterozygote expressed similar amounts of Myc-tagged Ax allele product as endogenous protein from the normal allele.
(f) The Myc-tagged deltaC6 product was expressed at approximately 3 to 4-fold lower levels than the endogenous protein from the normal allele.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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