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Gene Expression Data
Assay Details
Assay
Reference: J:63601 Heiss NS, et al., Gene structure and expression of the mouse dyskeratosis congenita gene, dkc1. Genomics. 2000 Jul 15;67(2):153-63
Assay type: RNA in situ
MGI Accession ID: MGI:3839452
Gene symbol: Dkc1
Gene name: dyskeratosis congenita 1, dyskerin
Probe: Clone M152397
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present 3a
TS17: yolk sac Strong Single cells 3a Expression is in mesodermal cells adjacent to aggregates of unlabeled primitive erythroblasts in the yolk sac.
TS17: extraembryonic component Strong Regionally restricted 3a Expression is in the Reichert membrane.
TS28: placenta Strong Regionally restricted 3a Expression is in the Reichert membrane.

Specimen 3c: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: yolk sac Strong Single cells 3c Expression is in mesodermal cells adjacent to aggregates of unlabeled primitive erythroblasts in the yolk sac.
TS17: extraembryonic component Strong Regionally restricted 3c Expression is in the Reichert membrane.

Specimen 3d: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: yolk sac Strong Single cells 3d Expression is in mesodermal cells adjacent to aggregates of unlabeled primitive erythroblasts in the yolk sac.

Specimen 4a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: surface ectoderm Present 4a
TS17: limb ectoderm Strong 4a

Specimen 4c: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: skin Present 4c
TS21: limb epithelium Strong 4c
TS21: vibrissa Strong 4c

Specimen 5a: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: embryo Present Ubiquitous 5a

Specimen 5b: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: embryo Present Ubiquitous 5b
TS24: nasal cavity epithelium Strong 5b
TS24: spinal cord Strong 5b
TS24: telencephalon Strong 5b

Specimen 6a: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: nasal cavity epithelium Strong 6a

Specimen 6c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: intestine epithelium Strong 6c

Specimen 6e: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: skin Strong 6e
TS22: hair follicle Strong Regionally restricted 6e Expression is in the outer root sheet.

Specimen 7a: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens epithelium Strong 7a
TS22: retina Strong 7a

Specimen 7c: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: telencephalon mantle layer Strong 7c
TS24: telencephalon marginal layer Strong 7c
TS24: telencephalon ventricular layer Strong 7c

Specimen 7e: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Strong 7e

Specimen 7g: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal ganglion Strong 7g

Specimen Not shown E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present Non-Uniform Expression was in all tissues throughout development from 9.5 to 18.5 dpc with higher levels of expression in tissues of epithelial and neuroectodermal origin.

Specimen Not shown E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: embryo Present Non-Uniform Expression was in all tissues throughout development from 9.5 to 18.5 dpc with higher levels of expression in tissues of epithelial and neuroectodermal origin.

Specimen Not shown Newborn: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: mouse Strong Non-Uniform Higher levels of expression in tissues of epithelial and neuroectodermal origin.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory