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Gene Expression Data
Assay Details
Assay
Reference: J:138798 Rock JR, et al., Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn. 2008 Sep;237(9):2566-74
Assay type: RNA in situ
MGI Accession ID: MGI:3822014
Gene symbol: Ano1
Gene name: anoctamin 1, calcium activated chloride channel
Probe: Tmem16a cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trachea epithelium Present 2A
TS20: lung epithelium Present Regionally restricted 2A Expression is absent in the distal tip.

Specimen 2B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present Regionally restricted 2B Expression is absent in the distal epithelium.
TS22: lung mesenchyme Present Regionally restricted 2B Expression is in the mesenchyme surrounding the bronchiolar epithelium.

Specimen 2C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung epithelium Present 2C
TS24: rib Present Regionally restricted 2C Expression is in the perichondrium.
TS24: lung mesenchyme Absent 2C

Specimen 2D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung epithelium Present Regionally restricted 2D Expression is in the epithelium of the terminal saccules.

Specimen 3A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: esophagus mesenchyme Present Regionally restricted 3A Expression is in the submucosa.
TS24: aorta Present 3A
TS24: thymus Present 3A
TS24: trachea epithelium Present 3A
TS24: trachea mesenchyme Present Regionally restricted 3A Expression is in the mesenchyme immediately dorsal to the trachea.
TS24: esophagus epithelium Absent 3A

Specimen 3B,C: embryonic day 14.5 (more )
Note: (C) Is a higher magnification of the small intestine shown in (B).
Structure Level Pattern Image Note
TS22: metanephros Present 3B
TS22: pancreas Present 3B
TS22: stomach mesenchyme Present 3B
TS22: ureter Present 3B
TS22: stomach epithelium Present Regionally restricted 3B Expression is in the posterior stomach.
TS22: intestine mesenchyme Present Regionally restricted 3B , 3C Small intestine.
TS22: intestine epithelium Weak Regionally restricted 3B , 3C Small intestine.

Specimen 4A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Weak Regionally restricted 4A Expression is in the dorsal neural tube.
TS22: vertebral cartilage condensation Weak Regionally restricted 4A Expression is in the perichondrium of the neural arch of a vertebra.

Specimen 4B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: dorsal aorta Present 4B
TS22: thymus primordium Present 4B
TS22: trachea mesenchyme Present Regionally restricted 4B Expression is in the mesenchyme dorsal to the trachea.

Specimen 4C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: esophagus Present 4C
TS24: thymus Present 4C
TS24: trachea epithelium Present 4C
TS24: rib Present Regionally restricted 4C Expression is in the perichondria.
TS24: vertebra Present Regionally restricted 4C Expression is in the perichondria.
TS24: trachea mesenchyme Present Regionally restricted 4C Expression is in the mesenchyme dorsal to the trachea.

Specimen 5A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: epidermis Present Regionally restricted 5A Expression is in the basal layers.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory