Rb1 Western blot Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:124353 Landis MW, et al., The LxCxE pRb interaction domain of cyclin D1 is dispensable for murine development. Cancer Res. 2007 Aug 15;67(16):7613-20
Assay type:	Western blot
MGI Accession ID:	MGI:3800881
Gene symbol:	Rb1
Gene name:	RB transcriptional corepressor 1

Antibody:	anti-RB (clone G3-245)
Detection system:	Secondary antibody coupled to horseradish peroxidase

Results

Image: 5B

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Genetic Background	Mutant Allele(s)	Sex
+/+	P1	TS27: retina	Present	either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6J)		Not Specified
-/-	P1	TS27: retina	Present (a)	involves: 129P2/OlaHsd	Ccnd1^tm1Dsn/Ccnd1^tm1Dsn	Not Specified
+/+	P1	TS27: retina	Present	either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6J)		Not Specified
delta/delta	P1	TS27: retina	Present (b)	either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6J)	Ccnd1^tm2Phin/Ccnd1^tm2Phin	Not Specified

Notes:
(a) pRb was present primarily in its hypophosphorylated form in retinas from cyclin D1 knockout animals.
(b) Expression in this mutant is the same as in wild-type. There is an abundance of hyperphosphorylated ppRb.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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