Gene Expression Data
Assay Details
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Assay
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Reference:
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J:55455
Kitamura K, et al., Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism. Development. 1999 Dec;126(24):5749-58
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:3798941
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Gene symbol:
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Pitx2
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Gene name:
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paired-like homeodomain transcription factor 2
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Reporter:
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lacZ
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Direct Detection
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Assay notes:
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Fixative: 0.2% glutaraldehyde/1% formalin/0.02% NP-40.
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Results
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Specimen
7F:
embryonic day 13.5; Pitx2tm1Kki/Pitx2 +
(more  )
Specimen
7F:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Pitx2tm1Kki/Pitx2+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Specimen
7G:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL
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Mutant Allele(s):
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Pitx2tm1Kki/Pitx2tm1Kki
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: extrinsic ocular pre-muscle mass |
Absent |
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7G
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LacZ-positive cells could not be found in the extraocular muscle forming region.
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| TS21: cornea |
Present |
Regionally restricted |
7G
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Thickening of the lacZ positive mesothelial layer of the cornea was seen between cuboidal epithelium making up the anterior part of the lens and cornea ectoderm.
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Analysis Tools
